86 citations,
October 2017 in “Clinics in Dermatology” Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
[object Object] 30 citations,
December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
16 citations,
March 2018 in “Seminars in Oncology” The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.
2 citations,
January 2011 in “Elsevier eBooks” Early treatment of acne is crucial to prevent scarring and psychological effects.
1 citations,
August 2020 in “Food Research” Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
April 2024 in “Cell death and differentiation” Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
June 1996 in “Irish Journal of Medical Science (1971 -)” The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.
165 citations,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
[object Object] 100 citations,
March 2006 in “Journal of biological chemistry/The Journal of biological chemistry” Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
50 citations,
January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
36 citations,
August 2011 in “Journal of Controlled Release” Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
31 citations,
January 2011 in “Dermato-endocrinology” Melatonin protects skin against UV damage by regulating various cellular processes.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
16 citations,
September 2018 in “Journal of Ethnopharmacology” Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
13 citations,
July 2019 in “Pediatric dermatology” Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.
6 citations,
July 2023 in “Nature cell biology” SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
6 citations,
July 2013 in “Experimental and Therapeutic Medicine” Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
September 2023 in “Frontiers in cell and developmental biology” Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
62 citations,
July 2022 in “Science Immunology” TREM2 macrophages and unsaturated lipids contribute to acne inflammation.
5 citations,
February 2022 in “Seminars in cell & developmental biology” Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
4 citations,
May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.