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Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.

Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

PCOS is a complex condition that affects women's hormonal balance and metabolism, requiring lifestyle changes and medical management.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

Taking metformin with intense pulsed light therapy improves hair removal for women with PCOS.

Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.

Endocrine diseases in children often cause skin changes like dryness, redness, acne, hair loss, and more.

The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

A mutation in the Soat1 gene causes hair structure defects and other health issues in AKR/J mice.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

High proliferative activity and peripheral invasion indicate malignancy in canine sebaceous gland tumors; the term 'epithelioma' should be updated for clarity.

New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Adenosine complex helps increase hair thickness and density in hair loss.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Finasteride effectively treats baldness but may cause sexual side effects.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.