854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
71 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
56 citations,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
11 citations,
January 2018 in “International journal of trichology” Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.
9 citations,
January 2018 in “Hair transplant forum international” Researchers concluded that safe hair follicle extraction limits in FUE vary by individual characteristics and proposed a method to calculate these limits to maintain appearance.
6 citations,
September 2012 in “Our Dermatology Online” Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
4 citations,
August 2020 in “Journal of proteomics” Hair protein composition is similar across different races and shapes.
3 citations,
January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
3 citations,
June 2023 in “Medicines” Some antiseizure medications can cause reversible hair loss, with valproate, lamotrigine, and carbamazepine being the most common.
2 citations,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
2 citations,
January 2022 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Chemical hair straighteners can cause scalp and hair damage, but long-term effects are unclear.
2 citations,
July 2021 in “Genes” A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
2 citations,
March 2018 in “ACS Sustainable Chemistry & Engineering” Heating human hair creates hollow microtubes with smooth surfaces.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
July 2024 in “Journal of Dermatological Treatment” Botanical extracts and Minoxidil improved hair condition in a boy with a genetic disorder.
Higher levels of β-carotene and vitamin E may help prevent certain types of hair loss.
The KRT84 gene is linked to better wool quality in Gansu Alpine Fine-wool sheep.
May 2021 in “American journal of medical sciences and medicine” Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.
January 2023 in “Operative Techniques in Otolaryngology-Head and Neck Surgery” Hair transplants help transgender patients look more like their gender identity, with different procedures for trans women and men.
4 citations,
May 2013 in “Dermatologic Surgery” Three new techniques simplify and improve the preparation of tissue samples for skin cancer surgery.
Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.
205 citations,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
41 citations,
November 2011 in “The Journal of Dermatology” Some hair loss disorders are caused by genetic mutations affecting hair growth.
19 citations,
August 2011 in “Archives of Dermatology” CCCA is a common scarring hair loss in African descent women, possibly linked to genetics, hair care practices, and health issues like diabetes.
9 citations,
February 2018 in “The Journal of Dermatology” A new mutation in the LIPH gene was found to cause a rare hair disorder in a Japanese boy.
January 1997 in “Elsevier eBooks” Hair and nails are skin parts that develop early and serve protective and functional roles.
Different scalp and hair disorders are more common in certain ethnic groups, with the most common being androgenetic alopecia, which is treated with medications like minoxidil and finasteride.
114 citations,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
88 citations,
July 2014 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.