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A new mouse mutation causes skin and hair issues, influenced by another gene.

In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.

This study identifies iRhom2 as a crucial regulator of hair follicle differentiation, showing that the iRhom2Uncv mutation leads to dysplasia and reduced TACE maturation, resulting in a hairless phenotype in mice.

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

In this study, a methanol extract of Eclipta alba was found to have dose-dependent hair growth-promoting activity in C57BL6 mice.

Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.

This genetic study identified a potential interval for the Marie Unna hypotrichosis gene but found no mutations in the nearby hr gene, suggesting its involvement remains unconfirmed.

This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.

This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.

This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.

This study found that mutant mice with the we/we wal/wal genotype exhibit significant defects in hair shaft structure and epidermis stratification, correlating with postnatal alopecia symptoms.

This study found that loss of Apc due to K14-cre-mediated gene recombination in mice led to aberrant growth in ectodermally derived squamous epithelia, implicating its critical role in specifying epithelial cell fates during embryonic development.

This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.

This article discusses the minimal research on hair growth physiology and highlights Dr. Masumi Inaba's contributions to understanding androgenetic alopecia, but reports no new experimental results.

This article discusses treatment approaches for female pattern hair loss and concludes that available medical treatments are effective in reversing or stabilizing the condition in most cases of mild-to-moderate severity.

This review discusses the roles of adiponectin and bradykinin in skin homeostasis and pathologies, highlighting the need for further research into their therapeutic potential but reports no new clinical results.

This review highlights the increasing use of trichoscopy, a noninvasive and well-tolerated diagnostic tool, to aid in the accurate diagnosis and management of various pediatric hair and scalp conditions, such as alopecia and other abnormalities.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

In a transgenic mouse model, this study found that overexpression of keratin 16 in skin keratinocytes led to hyperkeratosis and increased EGF receptor signaling, altering skin cell behavior and structure.

This review emphasizes that collaboration between forensic anthropology and molecular anthropology could significantly improve the identification of unknown human remains by creating more comprehensive biological profiles.

This study explores the development of a herbal hair oil formulation using selected herbs to potentially address hair loss and related issues, as an alternative to synthetic medications that may cause serious side effects and offer limited effectiveness.

This article reviews different grafting strategies for hair restoration surgery in extensive baldness and suggests uniform density grafting offers less detectable results, especially under adverse grooming conditions.

This article reviews 25 years of hair restoration advancements, highlighting the shift towards techniques that emphasize naturalness and undetectability, and reports no new research findings.

This study found that 32% of patients with hereditary male pattern baldness experienced cosmetically acceptable hair growth after applying topical minoxidil twice daily, with no serious side effects reported.

This review outlines a systematic method for diagnosing hair loss and presents no new findings; the authors emphasize the importance of biopsy in cicatricial alopecia cases.

This article discusses diagnostic challenges and management approaches for hair loss in women of color, emphasizing the importance of clinical examinations and education to prevent and manage traction alopecia.

This article discusses various hair diseases and emphasizes their significant impact despite affecting a small area, but does not report new clinical findings.

This study describes the use of automatic Biofibre® hair implants as a surgical technique for hair restoration, offering immediate aesthetic results for men and women with hair loss or thinning, provided certain conditions for success are met.