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Genetic mutations cause various hair diseases, and whole genome sequencing may reveal more about these conditions.

This article discusses current non-hormonal and topical treatments for androgenic hair loss but reports no clinical results; the authors highlight micrograft reimplantation as the only method that produces noticeable hair density improvements.

In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.

This study investigated a new treatment for androgenetic alopecia using curcumin-primed milk-derived extracellular vesicles in a mouse model, finding that these vesicles improved hair follicle health and promoted hair regeneration by modulating key signaling pathways and reducing inflammation.

In a mouse model of androgenetic alopecia, this study developed a treatment combining a copper-curcumin nanoparticle oleogel with traditional Gua Sha therapy, which augmented hair regeneration more effectively than minoxidil by improving the follicular microenvironment and regulation of inflammatory responses.

This study found that encapsulating ascorbyl palmitate in curcumin-grafted nanoparticles increased its stability compared to unencapsulated forms, with primary skin penetration occurring through hair follicles in pig skin.

This study found that curcumin spanlastics demonstrated greater antimicrobial, antioxidant, and anticancer activities in the MCF-7 breast cancer cell line compared to curcumin alone or curcumin nanocrystals, also affecting several cancer-related protein markers and showing enhanced solubility and activity.

In this study, researchers synthesized biomedical polyurethanes incorporating curcumin and varying PEG content to enhance water solubility and control curcumin release, finding that higher PEG content improved hydrophilicity, swelling, and degradation, while maintaining excellent antioxidant and antibacterial activities, suggesting promise for biomedical applications.

In this study, the researchers developed and optimized a curcumin nanocrystal gel to enhance skin permeability, reporting improved dissolution properties and antiproliferative effects on cell lines, suggesting it as a promising topical delivery system.

In this study, researchers developed iron-curcumin-coordinated nanoparticles to enhance curcumin's bioavailability and therapeutic effects, finding that these nanoparticles accelerate wound healing in diabetic mice by reducing inflammation and oxidative stress more effectively than free curcumin.

In an animal study with a skin defect model, this research reported that curcumin-loaded hydrogels made from recombinant humanized collagen and an eco-friendly crosslinker enhanced wound repair by promoting angiogenesis, granulation tissue formation, and hair follicle neogenesis, while providing antioxidant benefits.

In this study, a mechanical model was developed to describe and validate the effectiveness of overnight hair curling, suggesting that combining it with hair fixatives can maintain a desired curl for over a day.

This study mapped the curly mutation in mice to a specific region on chromosome 11, identifying it as a candidate model for studying human genetic hair disorders.

This review highlights that stem cell-based therapies show promise in skin regeneration for conditions like chronic wounds and burns due to their regenerative and immunomodulatory effects, though challenges like safety and scalability limit widespread clinical use.

This narrative review reports that tissue-engineered scaffolds for wound healing generally match standard care outcomes, with some trials indicating faster healing and improved scar quality, despite challenges like limited cellular infiltration and inadequate vascularization.

This review suggests that curcumin and piperine may offer a promising multi-target therapeutic approach for alopecia by simultaneously modulating androgenic and inflammatory pathways, though experimental and clinical validation are necessary to confirm their efficacy.

In this review, researchers explored the potential of a curcumin–piperine combination in alopecia management through computational analyses, highlighting its capacity to modulate multiple pathways involved in hair follicle homeostasis, although further experimental and clinical validation is necessary to confirm its efficacy.

This study found that a combination of curcumin and piperine demonstrated moderate antioxidant activity, negligible cytotoxicity, and significant potential for promoting hair regrowth in rat models of alopecia, suggesting it could be a safe and effective natural alternative for managing hair loss.

This review reports that Janus kinase inhibitors and regenerative therapies, such as exosomes and platelet-rich plasma, significantly improve scalp hair regrowth in moderate-to-severe alopecia areata, though challenges like high relapse rates and socioeconomic barriers remain, underscoring the need for personalized treatment protocols.

In this study, researchers developed and tested an eco-friendly herbal hair gel containing extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 excelled in viscosity, spreadability, extrudability, antifungal activity, and stability, making it a promising sustainable alternative to synthetic hair gels.

This study formulated and tested eco-friendly herbal hair gels using extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 showed optimal viscosity, spreadability, superior antifungal activity, and stability over six months, making it a promising sustainable alternative to synthetic hair gels.

In this study, researchers observed a curvilinear relationship between loneliness and hair cortisol concentration among older adults at elevated cardiovascular risk, with cortisol levels higher at low-to-moderate loneliness and lower at higher loneliness, though results were sensitive to some data exclusions.

This review discusses PRP therapy's history, mechanisms, and innovations in its use across various medical fields, but provides no new clinical results; the authors highlight challenges like standardization and regulatory issues.

This study evaluated a polyherbal hair oil with extracts from five medicinal plants and found that formulation F2 had an optimal balance of stability and potential benefits for hair growth and scalp health, maintaining stable physicochemical properties over six months.

In this study, the researchers developed a polyherbal hair oil and found that one formulation, F2, was stable and had an optimal balance of ingredient concentrations, showing potential for promoting hair growth and maintaining scalp health.

This review reports that lifestyle modification, including diet and exercise, is essential for managing PCOS, while pharmacological and complementary treatments address specific symptoms like menstrual irregularities and insulin resistance.

This review reports that collagen as a nutraceutical shows promising results for improving skin health in estrogen-deficient women, but more research is needed for scalp hair, nail health, and optimal dosing of curcumin and glutathione.

This review highlights advancements in vitiligo treatment, noting improved diagnostic techniques and the emergence of targeted therapies like Janus Kinase inhibitors, which may offer more effective management of this complex autoimmune skin disorder.

This review reports no new clinical results but summarizes the therapeutic potential of Aloe-derived extracellular vesicles in tissue repair, highlighting both promising mechanisms and the need for further research into their clinical application.

This study evaluated formulations of a cream containing turmeric and ginger extracts for inhibiting underarm hair growth, finding that the formulation with 15% stearic acid and 3% triethanolamine had the most optimal physical characteristics and potential for cosmetic development.