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The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Low ferritin levels can indicate iron deficiency as a cause of hair loss.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

PRP treatment may stimulate hair growth by promoting blood vessel formation, increasing growth factors, and preventing cell death.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Plant-based ingredients are effective and safe for modern skincare products.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

New treatments for hair loss may target specific pathways and generate new hair follicles.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.