48 citations
,
March 2020 in “Stem Cell Research & Therapy” This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
87 citations
,
December 2004 in “Dermatology” This review discusses the term "skin pore," its different meanings, and current methods to objectively describe skin pores, but reports no new clinical findings.
3 citations
,
November 2017 in “The American Journal of Cosmetic Surgery” This study evaluated donor area scars in hair restoration using a new assessment scale and found that most patients had good quality scars, with average scores of 15 or less out of 40.
July 2024 in “Fitoterapia” This study found that Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose improved androgenetic alopecia symptoms in mice by reducing DHT levels and activating specific hair growth pathways.
January 2010 in “Journal of Animal Science” This study demonstrated that transcutaneous vaccination via cyanoacrylate skin surface stripping effectively induced both CD4 and CD8 T cell responses in humans, offering a promising alternative to intramuscular injection.
3 citations
,
May 2024 in “BMC Medical Genomics” This study is the first to identify a de novo heterozygous frameshift insertion variant in the ARID1B gene as a cause of Coffin-Siris syndrome with an association to excessive early-onset high myopia.
30 citations
,
January 2014 in “Journal of Controlled Release” This study concluded that combining cyanoacrylate skin surface stripping with particle-based antigen delivery effectively targets HIV-1 p24 protein to skin cells, supporting its potential for needle-free transcutaneous vaccination.
December 2013 in “Pump Industry Analyst” This study found that using particle-based antigen delivery in combination with cyanoacrylate skin surface stripping is an effective needle-free method for targeting HIV-1 p24 protein to skin cells, enhancing transcutaneous vaccination potential.
7 citations
,
April 2021 in “Journal of Bodywork and Movement Therapies” This editorial reviews the concept of central sensitization and central sensitivity syndromes, discussing their potential role linking various chronic conditions, but it reports no new clinical findings.
In this study, women with polycystic ovary syndrome showed higher scores in character strengths like hope and judgement compared to those without PCOS.
October 2013 in “Journal of the American College of Cardiology” This study found that individuals with a nondipper blood pressure pattern had higher 24-hour urinary aldosterone levels, suggesting a possible link to heart issues.
January 2024 in “La Ciencia al Servicio de la Salud y Nutrición” This narrative review attributes antiandrogenic properties to spironolactone, reporting its effectiveness in treating dermatological conditions like alopecia androgenica, acne, and hirsutism, though highlighting necessary attention to potential adverse effects and contraindications.
July 2024 in “LA CIENCIA AL SERVICIO DE LA SALUD Y NUTRICIÓN” In this report, a newborn female with bilateral symmetrical alopecia lesions was diagnosed with congenital triangular alopecia, an unusual presentation, highlighting the disorder's benign nature and the importance of early recognition and conservative management.
29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” This review discusses the potential of using high-throughput and high-content screening methods for drug repositioning in rare diseases and reports no new results.
20 citations
,
May 2020 in “Experimental Dermatology” This review discusses age-related changes in scalp skin and their potential effects on hair follicle aging, but reports no new clinical results, calling for further investigation.
20 citations
,
December 2011 in “Journal of inherited metabolic disease” This study found that valproic acid may interfere with the leucine metabolic pathway by inhibiting 3-methylcrotonyl-CoA carboxylase and biotinidase, which could contribute to side effects like skin rash and hair loss in patients.
19 citations
,
July 2015 in “Journal of inherited metabolic disease” This study observed that while betaine supplementation decreases total homocysteine and increases methionine levels in a mouse model of CBS deficiency, it is not as effective as methionine restriction in reversing associated phenotypes.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
27 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified somatostatin as a potential secretory factor contributing to the immune privilege of human hair follicles.
23 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.
8 citations
,
March 2017 in “Experimental Dermatology” In this exploratory study, researchers found slightly increased levels of inflammatory markers in scalp skin affected by androgenetic alopecia, suggesting differential gene expression involved in hair cycle and keratin production.
4 citations
,
November 2017 in “Journal of Cosmetic Dermatology” This study found that polyquaternium-68 at pH 9 achieved the greatest hair deposition, while polyquaternium-44 demonstrated the best wash resistance at pH 6.
1 citations
,
June 2015 in “Australasian Journal of Dermatology” This case report describes a patient with Cronkhite–Canada syndrome, where immunosuppression and nutritional support led to disease remission.
January 2023 in “World Journal of Clinical & Medical Images” This report discusses a late-onset case of Cronkhite-Canada syndrome that improved with prednisone treatment, highlighting the importance of early diagnosis to reduce life-threatening complications.
September 2016 in “Annals of occupational and environmental medicine” In this study, cleanroom workers in a secondary battery factory reported worse dermatologic life quality compared to non-cleanroom workers, as measured by the Skindex-29 questionnaire.
402 citations
,
August 2011 in “Cancer research” This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.
324 citations
,
July 2020 in “Applied Water Science” This study found high levels of toxic heavy metals in water sources of mining communities in Abakaliki, Nigeria, posing potential health risks including Parkinson's and Alzheimer's diseases.
243 citations
,
September 2016 in “Dermatology and Therapy” This article provides an overview of how dermoscopy can aid in the noninvasive diagnosis of various general dermatological disorders, grouped by clinical presentation, but reports no new clinical results.
213 citations
,
June 2017 in “Rheumatology” This guideline outlines the management of systemic lupus erythematosus in adults but reports no new clinical findings.