64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
61 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” This review examines beta-catenin's role in stem cell renewal, lineage selection, and tumor formation in the epidermis and reports no new experimental findings.
57 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
47 citations
,
June 2012 in “Genes & Development” This study found that maternal consumption of a western diet in mice led to toxic milk production, causing inflammation and alopecia in nursing neonates due to Toll-like-receptor activation.
46 citations
,
December 2018 in “Genes & Development” This review discusses lung regeneration and highlights the role of facultative stem/progenitor cells, but it reports no new findings and calls for further exploration of underlying mechanisms.
44 citations
,
April 2017 in “Genes & development” This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” This abstract omits specific findings and does not provide new research results.
40 citations
,
April 2014 in “Genes & Development” The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.
36 citations
,
June 1988 in “Australian Journal of Biological Sciences” This study found that twice-daily intradermal injections of mouse epidermal growth factor in Merino sheep resulted in dose-dependent changes in wool follicles and fibres, including induction of catagen and subsequent regeneration.
32 citations
,
December 2014 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of polarity proteins in epidermal morphogenesis and homeostasis and discusses how their alteration may contribute to skin disease, but reports no new experimental findings.
27 citations
,
June 2013 in “Genes & development” This study found that L-type channel blockers can induce hair growth in Timothy syndrome by overcoming delays in anagen phase, suggesting a potential therapeutic role for tissue regeneration.
25 citations
,
June 2019 in “Endocrine Related Cancer” This review discusses the structure and function of steroid nuclear receptors, particularly focusing on androgen receptor dysregulation in prostate cancer and androgen insensitivity syndromes, without reporting new experimental results.
24 citations
,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
15 citations
,
January 1999 in “Reproduction Fertility and Development” This study conclusively demonstrated that in Merino fetuses, secondary follicle initiation is completed several weeks before birth, with a peak 16 days prior and lower levels observed at and after birth.
12 citations
,
February 2019 in “Skin research and technology” This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.
11 citations
,
January 1987 in “Australian Journal of Experimental Agriculture” In this study, Australian cashmere goats receiving protein supplements maintained their weight and showed increased fleece growth, though cashmere growth was largely unaffected.
9 citations
,
February 1981 in “Australian journal of biological sciences” This study found that crossbred lambs fed liquid diets with reconstituted cow's milk initially grew wool without crimp, with crimp resuming two weeks post-weaning.
9 citations
,
December 1978 in “Australian Journal of Biological Sciences” This study found that flumethasone administration in Merino wethers led to variations in wool shedding and initial reductions in wool growth, with full recovery generally observed within 60 days post-treatment.
7 citations
,
March 2019 in “Journal of cosmetic dermatology” This study found that African and Caucasian hair contain the most lipids, and depletion of these lipids leads to less water retention and increased water desorption, with Caucasian hair showing improved breaking tenacity after lipid extraction.
7 citations
,
October 2013 in “Methods in molecular biology” This article describes standard methods for studying DNA methylation dynamics in mouse skin and hair follicle stem cells but presents no new research findings.
7 citations
,
April 2013 in “Animal Production Science” This study found that manipulating maternal cortisol levels during pregnancy altered Merino sheep wool characteristics, increasing fibre length and reducing crimp frequency in the offspring.
7 citations
,
February 1982 in “Australian Journal of Biological Sciences” This study observed that cell aggregates formed rapidly in cultures of rat hair follicle cells, with proteins showing hair cortical keratin but not synthesizing it as anticipated.
5 citations
,
May 1983 in “Australian journal of biological sciences” This study found that concurrent administration of cycloleucine with ethionine prevented the weakening of wool fibers in sheep, whereas reduced glutathione did not have the same effect.
4 citations
,
May 1981 in “Australian Journal of Biological Sciences” This study observed that rat dermal tissue cultures, rich in hair follicle cells, produce various glycosaminoglycans, including hyaluronic acid and dermatan sulfate, which change in synthesis and sulfation patterns over time.
3 citations
,
September 2023 in “PeerJ Computer Science” This study introduced an innovative metric for assessing college students' mental health, incorporating temporal perception and a hybrid clustering algorithm, and found it achieved over 90% accuracy, outperforming existing methods in evaluating mental health during public health challenges.
3 citations
,
June 2013 in “Genes & development” In their research, Yucel and colleagues found that CaV1.2 is expressed in hair follicle stem cells, facilitating anagen re-entry in a way not dependent on calcium flux.
3 citations
,
January 1982 in “Australian journal of biological sciences” This study found that ethionine significantly inhibited wool growth in sheep, with L- and D-isomers being equally effective, but did not cause hair loss in sucking mice or rats.
2 citations
,
December 2014 in “Journal of primary health care” This review of polycystic ovary syndrome cases in New Zealand suggests a need for improved recording of diagnostic criteria, as general practitioners often rely on ultrasounds despite guidelines advising otherwise.
2 citations
,
January 2012 in “Charles Sturt University Research Output (CRO)” This study found that during pregnancy, dairy cattle experienced an increase in body hair diameter and weight; however, after giving birth, the hair weight decreased.
2 citations
,
January 1960 in “Australian Journal of Biological Sciences” The Naked gene in mice causes abnormal sebaceous glands and disrupts hair follicle organization.