Search

everythinglearnresearchcommunity

for

Search:↓

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

The protein FLCN is involved in cellular cleanup and is regulated by ULK1.

The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Three new finasteride solvates found, change forms under different drying conditions.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Tadalafil and Finasteride may help treat aggressive melanoma.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

New hybrid compound found to effectively prevent hair loss.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.

Microemulsions could improve how drugs are delivered and absorbed in the body.

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Lack of cystatin M/E causes thin hair and dry skin.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The new hydrogel is good for wound dressing because it absorbs water quickly, has high porosity, can release drugs, fights bacteria, and helps wounds heal with less scarring.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Human hair keratin might be good for filtering out harmful substances from water.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Natural compounds, especially Withaferin-A, may help treat post-COVID-19 complications, but some may have side effects.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.