research The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo
Apremilast may help treat hair loss in alopecia areata.
Search
for
Sort by
Research
240-270 / 1000+ resultsresearch The site of uptake of iodine by hair
Iodine is absorbed by hair just below the skin surface.
research Tumour development in Lynch syndrome : genes load the gun, lifestyle pulls the trigger?
This thesis suggests that for individuals with Lynch syndrome, factors such as dietary inflammatory potential and height do not significantly influence tumor development, while higher BMI at a young age may increase cancer risk in women.
research 809 IL-13 protein concentrates in the epidermis of lesional and non-lesional skin of AD patients
IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.
research Assessment of the efficacy and tolerability of a topical formulation containing caffeine and Procapil 3% for improvement of male pattern hair loss
This study found that a 12-week topical treatment with a caffeine and Procapil 3% formulation effectively reduced hair loss by 26.9% and improved hair growth in men with androgenetic alopecia, without any reported adverse effects.
research Clinical Case Notes. Retinoblastoma, microphthalmia and the chromosome 13q deletion syndrome
This case report indicates that retinoblastoma can occur in a microphthalmic eye and recommends using multiple imaging techniques due to potential differences in calcification visibility.
research Citrullus colocynthisas the Cause of Acute Rectorrhagia
This case study reports that Citrullus colocynthis can cause severe gastrointestinal symptoms, including rectorrhagia and mucosal erosion, highlighting the need for awareness of its potential side effects.
research 852 Targeted deletion of crif1 in mouse skin epidermis impairs skin homeostasis
Deleting Crif1 in mouse skin disrupts skin balance and hair growth.
research Trichothiodystrophy
research The features of onychomatrimas on in vivo reflectance confocal microscopy
Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.
research In Vivo Reflectance Confocal Microscopy in General Dermatology: How to Choose the Right Indication
This review outlines the practical use of reflectance confocal microscopy in dermatology, detailing its applications and considerations for diagnosing various skin conditions, but reports no new findings.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.
research Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo
This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.
research Citalopram and finasteride with the lot number FI0510058-A have been voluntarily recalled by Greenstone, after a labelling error
research Evolving CRBN ligands enhance the drug-like properties of protein degraders
This review discusses the evolution of Cereblon ligands in PROTAC technology, highlighting chemical innovations that may enhance drug-likeness and applicability in protein degradation, while noting challenges and future research directions.
research Trichoscopy of Central Centrifugal Cicatricial Alopecia: A Retrospective Study and Literature Review
This study describes trichoscopic findings in 11 dark-skinned women with central centrifugal cicatricial alopecia and highlights the potential of trichoscopy for early diagnosis and treatment.
research Finasteride for Chronic Central Serous Chorioretinopathy
research P095 The Very Interesting Small Bowel Lesions of Cronkhite-Canada Syndrome
In this study, three cases of Cronkhite-Canada syndrome revealed small bowel mucosal lesions, but these findings did not correlate with clinical symptoms or steroid treatment outcomes.
research scRNA+TCR-seq Reveals the Proportion and Characteristics of Dual TCR Treg Cells in Mouse Lymphoid and Non-lymphoid Tissues
In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
research Cronkhite-Canada Syndrome (CCS)—A Rare Case Report
This report presents a case of Cronkhite-Canada syndrome in an elderly Indian male, adding to the approximately 450 cases documented worldwide, but introduces no new results about the condition.
research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis
Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.
research Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway
This study suggests that CTHRC1, a protein expressed in cardiac fibroblasts, may improve wound repair and prevent cardiac rupture after myocardial infarction by activating a specific signaling pathway.
research CLED: A Calcium-Linked Protein Associated with Early Epithelial Differentiation
research Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
This study found that valproic acid promoted hair re-growth in C3H mice by activating the Wnt/β-catenin pathway, suggesting its potential as a treatment for alopecia.
research The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches
In mouse models, this study showed that transplanted dermal papilla and dermal sheath cells can integrate into hair follicles, promoting hair growth and extended anagen phases, with their effectiveness influenced by factors such as immune response and cell passage number.
research Loss of Dicer in Newborn Melanocytes Leads to Premature Hair Graying and Changes in Integrin Expression
This study found that stress-induced inactivation of the enzyme Dicer in melanocytes can cause premature hair greying by preventing proper melanocyte placement and melanin transfer in mice, suggesting the Dicer-miR92b-ItgaV pathway as an important link between stress and grey hair.
research The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal–Epidermal Junction of Mouse Skin
In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.
research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs
This study found that TAZ promotes adipogenesis in goat adipose-derived mesenchymal stem cells by enhancing PI3K/AKT pathway activity, with overexpression boosting adipocyte formation and knockdown inhibiting it.
research The Shape and the Location of Forehead Hairline of Korean Males in Their 20s & 30s
This study found that the inverted U-shape hairline is the most common among Korean male adults in their 20s and 30s, with an increased prevalence of the M-shape in their 30s.