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Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

The document advises health care providers on how to support transgender and gender-diverse youth with appropriate care and referrals.

Gender identity can be more diverse than just male or female.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.