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Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Insulin resistance linked to obesity may increase COVID-19 severity.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

A gene deletion causes the "hairless" trait in Iffa Credo rats.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.

ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.

The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

The document explains the difficulty in diagnosing and treating brain diseases caused by the immune system and stresses the need for quick and accurate tests.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.