research Advances in Genetic and Molecular Understanding of Omenn Syndrome: Implications for the Future
Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.
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research Isolating Subpopulations of Human Epidermal Basal Cells Based on Polyclonal Serum Against Trypsin-Resistant CSPG4 Epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Inherited Disorders of the Hair
The document explains the genetic causes and characteristics of inherited hair disorders.
research Recommendations on Trichological Treatments During COVID-19 Pandemic
Use telemedicine and strict hygiene for safe hair and scalp treatments during COVID-19.
research Mutation-Specific siRNA Knockdown of GJB2: Potential Gene Therapy for Keratitis-Ichthyosis-Deafness Syndrome
Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
research Stabilizing Mutations of KLHL24 Ubiquitin Ligase Cause Loss of Keratin 14 and Human Skin Fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research Genetics
Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.
research Transcriptomics Identifies Potential Novel Therapeutic Targets in Androgenetic Alopecia
Found new possible treatments for hair loss.
research Stem Cell Dynamics, Migration, and Plasticity During Wound Healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research Skin Expression of Mammalian Target of Rapamycin and Forkhead Box Transcription Factor O1, and Serum Insulin-Like Growth Factor-1 in Patients with Acne Vulgaris and Their Relationship with Diet
Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.
research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
research Are the Cutaneous Manifestations During or Due to SARS-CoV-2 Infection/COVID-19 Frequent or Not? Revision of Possible Pathophysiologic Mechanisms
Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.
research Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function
Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research The Cycling Hair Follicle as an Ideal Systems Biology Research Model
The hair follicle is a great model for research to improve hair growth treatments.
research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development
Chemokine signaling is important for hair development.
research Cultured Human and Rat Tooth Papilla Cells Induce Hair Follicle Regeneration and Fiber Growth
Tooth papilla cells can help regenerate hair follicles and grow hair.
research Current Advances of Dendrobium Officinale Polysaccharides in Dermatology: A Literature Review
Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.
research Androgens and Antiandrogens: Impact on Women's Health and Hormone Replacement Therapy
Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.
research Office Diagnosis of Hair Shaft Defects
The document explains how to identify different hair problems using a microscope.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle
Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research CAG Repeat Testing of Androgen Receptor Polymorphism: Is This Necessary for the Best Clinical Management of Hypogonadism?
Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
research Serum Lipocalin-2 as an Insulin Resistance Marker in Patients with Polycystic Ovary Syndrome
Lipocalin-2 levels are higher in women with PCOS and may indicate insulin resistance.
research Emerging Drugs for Alopecia Areata: JAK Inhibitors
JAK inhibitors may soon be a safe and effective treatment for alopecia areata.
research Single-Cell Transcriptomics Reveals Lineage Trajectory of Human Scalp Hair Follicle and Informs Mechanisms of Hair Graying
The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
research Demethylation of Methionine and Keratin Damage in Human Hair
Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
research Next-Generation Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.