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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Special fiber materials boost the healing properties of certain stem cells.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Oestrogens are key for bone growth during puberty in both boys and girls.

Wnt ligands are crucial for hair growth and repair.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

EGFR is essential for normal hair development and follicle differentiation.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.