January 2026 in “International Journal of Current Research and Review” This review of Adiantum capillus-veneris highlights its traditional medicinal uses, rich phytochemical profile, and broad range of pharmacological activities, but emphasizes the need for more research to validate and expand its therapeutic applications.
November 2025 in “International Journal of Research in Medical Sciences” In this case study, the authors explored the management of ophiasis, a rare and challenging form of alopecia areata, in a 3-year-old boy using the Unani system of medicine, aiming to provide insights for treatment approaches.
This study reviews the pharmacological potential of Bacopa monniera, highlighting its extensive therapeutic effects such as antioxidant, anti-inflammatory, and memory enhancement properties, which are primarily attributed to its diverse bioactive compounds.
May 2023 in “Journal of pharmacognosy and phytochemistry” This study conducted a comprehensive pharmacognostic and phytochemical analysis of Sphagneticola calendulacea stem, identifying tannin-filled cells, various secondary metabolites, and significant physicochemical characteristics, which could aid in authenticating the plant for therapeutic use.
March 2023 in “Journal of Veterinary Medicine and Animal Health” This study in Kitui County, Kenya, identified histopathological lesions due to Cordylobia anthropophaga infestations in dogs, including parasitic granulomas and eosinophilic lymphadenitis, leading to severe health effects such as emaciation and potential death.
This abstract is from a website and does not provide any study results or findings to summarize.
835 citations
,
October 2008 in “Nature Genetics” Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
351 citations
,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.
63 citations
,
May 2011 in “Clinical cancer research” In this study, topical CUR61414 was effective in inhibiting basal cell carcinomas in mice, but no clinical activity was observed in human trials.
32 citations
,
August 2015 in “Journal of Investigative Dermatology” In this study using a mouse model, Prom1+ dermal papilla cells were found to regulate the size of the papilla via β-catenin communication but did not aid in dermal repair.
28 citations
,
September 2013 in “Journal of Investigative Dermatology” This research reviews the roles of dermal papilla signaling in hair follicle development and suggests new genetic tools could advance bioengineering therapies for alopecia, but it reports no new results.
26 citations
,
December 2017 in “Journal of Investigative Dermatology” This study found that the acceleration of endothelial to mesenchymal transition due to loss of Notch signaling led to delayed wound healing and increased scarring in skin wounds.
26 citations
,
July 2016 in “PLOS ONE” This study demonstrated that β-catenin signaling in CD133+ dermal papilla cells enhances postnatal hair growth by accelerating the proliferation and differentiation of keratinocytes in the murine hair cycle.
24 citations
,
January 2019 in “Theranostics” This study found that loss of the Pten gene in Lgr5+ hair follicle stem cells promoted squamous cell carcinoma formation through the Akt/β-catenin signaling pathway.
23 citations
,
June 2012 in “PLOS ONE” This study found that KLF4 expression in mouse hair follicle stem cells is important for effective cutaneous wound healing, with its knockdown leading to reduced stem cell populations and delayed healing.
20 citations
,
September 2019 in “Journal of Cosmetic Dermatology” This study found that combining stromal vascular fraction with PRP injections significantly improved hair density and reduced hair loss more effectively than PRP alone in patients with androgenetic alopecia.
16 citations
,
March 2008 in “Dermatologic Surgery” This review discusses the effects of hydrogen peroxide in clinical settings, highlighting a lack of data specifically for its use in hair transplant surgery and recommending further research.
11 citations
,
May 2021 in “Journal of Medical Virology” This review discusses sex differences in immune response to respiratory viral infections, including SARS-CoV-2, and highlights that hormones like estrogen may provide females with better protection, but it reports no new results.
3 citations
,
February 2025 in “Endocrine” This study emphasizes the necessity of confirming elevated testosterone levels detected by immunoassay with liquid chromatography-tandem mass spectroscopy before pursuing more complex diagnostic evaluations.
2 citations
,
July 2013 in “EDIS” This fact sheet discusses the impacts of zinc deficiency, including its effects on the immune system, cognitive function, and growth in children, and highlights the increased risk for those who consume alcohol excessively; it reports no new clinical results.
1 citations
,
October 2022 in “Scientific reports” This study found that nestin-expressing progenitor cells, capable of becoming ORS keratinocytes, are present in both developing and adult mouse hair follicles.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” This study found that cilostazol promoted hair growth in human dermal papilla cells and mouse models, suggesting its potential as a therapeutic target for alopecia treatment.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” In this study, D-OCT imaging revealed distinct structural and vascular changes in patients with frontal fibrosing alopecia, highlighting the technique's potential for diagnosing and monitoring the condition's activity.
1 citations
,
June 2013 in “Clinics in dermatology” This review discusses various phytochemicals with potential antialopecia properties and their modes of action, reporting no new experimental results.
1 citations
,
May 2002 in “British Journal of Dermatology” This article provides an overview of hair density, hair diameter, and the prevalence of female pattern hair loss but reports no new clinical findings.
June 2026 in “Journal of health economics and outcomes research” In this study, researchers found that ritlecitinib 50 mg offered a lower cost per responder than baricitinib 2 or 4 mg at both 24 and 52 weeks for treating severe alopecia areata, suggesting potential implications for reimbursement or formulary decisions.
August 2025 in “International Journal of Research Publication and Reviews” This review examines the regulatory frameworks and definitions of quasi-drugs in South Korea and Japan, where cosmeceuticals like medicated shampoos and anti-hair loss agents are developed and marketed, providing consumers with more hygienic and preventive care options under specific safety and effectiveness oversight.
July 2025 in “Australasian Journal of Plastic Surgery” In this guide, the authors describe a scalp incision technique that minimizes damage to hair follicles and results in barely noticeable scars in hair-bearing areas.
September 2023 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This research reported that the FDA approved Litfulo® (ritlecitinib) as the first oral treatment for severe alopecia areata in adolescents over 12 years old, with 23% of treated patients showing significant hair regrowth in clinical trials compared to 1.6% with placebo.