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Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.

Fat cells in the skin help start healing and form important repair cells after injury.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Fullerenes show potential in skin care but need more safety research.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Muscles and nerves that cause goosebumps also help control hair growth.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Inactive hair follicle stem cells help prevent skin cancer.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Hoxc genes control hair growth through Wnt signaling.

Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.