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research Five years after Keogh's review of regulation in the aesthetics sector, what has changed?
This review discusses the progress and ongoing challenges in implementing regulations for cosmetic interventions, reporting no new results and highlighting areas that still need improvement.
research Nonsurgical cosmetic practice and COVID-19
The COVID-19 pandemic has caused a 57% increase in interest in facial cosmetic procedures, leading to calls for better industry regulation and professional standards.
research Minoxidil may suppress androgen receptor-related functions
This study found that minoxidil suppressed androgen receptor functions and stability, suggesting its potential use in treating diseases related to the androgen-AR pathway.
research The U.K. approach to putting patient safety first when receiving non-surgical cosmetic therapies: The cosmetic practice standards authority
This review from the 2013 Keogh Review found that non-surgical cosmetic interventions in the UK are largely unregulated, leaving patients with little protection or recourse.
research The truth about level 7 qualifications: what are they and why should you care?
This article discusses misconceptions surrounding level 7 qualifications in aesthetic training and emphasizes the importance of selecting reputable training providers, without presenting new research results.
research A Review: Proteins Involved in the Major Symptoms of Polycystic Ovarian Syndrome
This review examines the role of certain proteins in the pathogenesis of polycystic ovary syndrome and reports no new results, emphasizing the potential for future diagnostic and therapeutic advancements.
research Manifesto for change: governance and regulation within the aesthetics industry
This article discusses the need for changes in governance and regulation within the aesthetics industry, focusing on creating standards and competency frameworks to ensure safe practices. Results are not reported in this summary.
research How the dental profession can reduce the risk profile in facial aesthetics
Dental professionals should ensure safety in facial aesthetics by being properly trained and registered.
research Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.
research Prostate specific antigen (PSA) in diagnosis of polycystic ovarian syndrome – a new insight
This study found that women with PCOS have higher total PSA levels than controls, and the total PSA level correlates positively with testosterone and free androgen index.
research Cyproteronacetat zur topischen Therapie androgenabhängiger Erkrankungen
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
research Submission to the College of Physicians and Surgeons of Ontario. Re: Human Rights in the Provision of Health Services (2022)
This submission discusses the updated CPSO policy on human rights in healthcare, suggesting it imposes excessive requirements on physicians objecting to certain services for ethical reasons, and recommends a unified protection of conscience policy.
research Physician Awareness of the Safe Use of Cyproterone Acetate in Europe: A Survey on the Effectiveness of Additional Risk Minimization Measures
In this study, most surveyed physicians were aware of the meningioma risk linked to cyproterone acetate monotherapy, but many did not recall receiving updated safety communications.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
This review discusses the expression of PSA in hormonally-regulated tissues and female malignancies, emphasizing its potential as a diagnostic biomarker and role in antidoping initiatives.
research Prostate Specific Antigen in Different Dermatoses Associated with Polycystic Ovary: Review Article
This review discusses the potential use of prostate specific antigen as a diagnostic marker for hyperandrogenism in polycystic ovary syndrome but reports no new clinical results and calls for further research.
research Clinical Approaches to PCOS: A Survey of the NASPAG Membership
This study found significant variability among NASPAG members in diagnostic approaches for PCOS, though there was more agreement on recommended first-line therapies such as oral contraceptives and lifestyle changes.
research Is prostate-specific antigen a potential new marker of androgen excess in polycystic ovary syndrome?
In this study, serum PSA levels were higher in women with PCOS, suggesting it may serve as a marker for hyperandrogenism in this condition.
research Cyproterone Acetate in the Treatment of Sexual Disorders: Pharmacological Base and Clinical Experience
This article reviews the use of cyproterone acetate for conditions like prostate cancer and sexual disorders, highlighting its effects on libido but reporting no new specific trial results.
research Association between PSA and leptin, adiponectin, HbA1c, or C-peptide among African-American and Caucasian men
In this study, PSA levels were significantly lower among African-American men with higher C-peptide levels and Caucasian men with higher HbA1c levels, suggesting a link between metabolic markers and prostate cancer detection.
research A Review on the Clinical Utility of PSA in Cancer Prostate
This review re-evaluates the role of Serum Prostate Specific Antigen in prostate cancer diagnosis, suggesting it is most reliable for detecting cancer recurrences after treatment.
research 1450 THE TRUE BENEFIT OF PSA-SCREENING: MODELING THE IMPACT OF TRIAL SETTING AND PROTOCOL ON MORTALITY
This study modeled how differences in trial settings and protocols, such as biopsy compliance and control arm screening, can explain the varying prostate cancer mortality reductions observed in the ERSPC and PLCO trials.
research Pharmacological basis for clinical use of antiandrogens
This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
research How not to detect prostate cancer
This article discusses the implications of finasteride on serum PSA levels and questions the routine recommendation for prostate biopsy at specific PSA thresholds, urging reevaluation of prostate cancer detection methods; it reports no clinical results.
research The SAHA Syndrome
This review discusses SAHA syndrome in women, characterized by seborrhea, acne, hirsutism, and/or androgenetic alopecia, and notes its similarity to polycystic ovary syndrome without reporting new clinical results.
research PHARMACOLOGICAL BASIS FOR CLINICAL USE OF ANTIANDROGENS
This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.
research 11 Treatment of hirsutism and acne with cyproterone acetate
This review examines androgen status in male and female obesity and its influence on the metabolic syndrome, but reports no new clinical results.
research Submission to the College of Physicians and Surgeons of Ontario Re: Professional Obligations and Human Rights
This submission critiques policies on "effective referral" for euthanasia and assisted suicide, highlighting potential threats to physicians' civil liberties and suggesting revisions to uphold freedom of conscience in medical practice.
research 43569 BSA and special area involvement informs psoriasis disease severity in a real-world population: patient characteristics and treatment patterns
This study suggests that using the International Psoriasis Council's classification, which includes body surface area, special areas, and treatment history, may identify more candidates for systemic therapy than by body surface area alone.
research Relationship of Serum Prostate Specific Antigen with Hirsutism in Women Having Polycystic Ovary Syndrome Belonging to the Province of Khyber Pakhtunkhwa, Pakistan
This study observed that women with PCOS from Khyber Pakhtunkhwa had significantly higher serum PSA levels, which positively correlated with hirsutism, testosterone, and DHEAS levels compared to healthy controls.