Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that using short durations of heat with chemical penetration enhancers improved isotretinoin delivery to human skin, especially via the hair follicles.

This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.

This study observed that carbon paste electrodes catalyze the electrooxidation of minoxidil more efficiently than other electrode types, with a detection limit of approximately 20 ng mL^-1.

This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.

This study found that short durations of heat and specific chemical penetration enhancers significantly improved the delivery of finasteride to human scalp skin and hair follicles.

This review found that anti-aging peptides show promise in cosmeceuticals due to their targeted actions to rejuvenate skin, but challenges like peptide stability, penetration, and limited clinical data limit their current effectiveness.

This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This review outlines computational strategies, including chemogenomics and drug repositioning, for coronavirus drug discovery and reports no new clinical findings; the authors highlight the advantages of these methods in rapidly identifying therapeutic candidates.

This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.

This study identifies five compounds, including gemcitabine and methylene blue, that inhibit SADS-CoV and suggests their potential for developing antiviral drugs against future outbreaks.

This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.

This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.

This study concluded that Metformin may be suitable for prophylaxis or mild COVID-19, while a combination of Oseltamivir, Tamoxifen, and Dexamethasone could benefit moderate to severe cases, highlighting the need for more trials on other drug candidates.

This review synthesizes research on hederagenin's anticancer and anti-inflammatory potential, emphasizing chemical modifications to enhance its bioactivity, but reports no new experimental findings.

In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.

Minoxidil helps hair regrowth in alopecia areata safely.

Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.

This study found that androgenic alopecia is the strongest predictor of coronary artery disease in young men from Western India, followed by premature graying and obesity.

This perspective highlights evidence suggesting inflammation plays a significant role in male and female pattern hair loss, indicating that targeting inflammatory pathways may improve future therapeutic options.

This perspective highlights the role of inflammation in male and female pattern hair loss and its implications for developing future therapeutic options.

This study observed a high prevalence of PCOS among young female-pattern hair loss patients and suggested that AMH levels might be more indicative of FPHL than traditional androgens.

This exploratory pilot study found that topical sildenafil and minoxidil both significantly increased hair counts in male patients with androgenic alopecia, with varying effects at different scalp regions.

This review highlights bicalutamide as a promising oral therapy for female pattern hair loss, noting its safety, tolerability, and effectiveness in women with hyperandrogenic symptoms like acne and hirsutism, though further trials are needed to confirm its ideal dose and efficacy.

The authors provide an overview of using topical minoxidil to manage female pattern hair loss in Indian clinical practice, emphasizing its significance as the main treatment method.

This study found that 448-kHz Capacitive-Resistive Electrothermal Therapy led to a significant increase in hair density in women with Female Pattern Hair Loss, likely due to stimulated proliferation of dermal papilla cells.

This study evaluated donor area scars in hair restoration using a new assessment scale and found that most patients had good quality scars, with average scores of 15 or less out of 40.

A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.