MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
9 citations,
April 2021 in “Frontiers in Immunology” Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
1 citations,
April 2020 in “medRxiv (Cold Spring Harbor Laboratory)” The study found that Tourette Syndrome may be linked to certain immune system processes and synaptic signaling.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain genetic variants in ERN1, TACR3, and SPPL2C are linked to when Alzheimer's disease starts.
109 citations,
April 2000 in “European Urology” Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
November 2019 in “Synapse” Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.
April 2019 in “International Journal of Research in Dermatology” Most women with hirsutism have mild symptoms and often experience acne, menstrual irregularities, and obesity.
September 2016 in “Hair transplant forum international” Methylene blue is less effective than normal saline solution for storing hair grafts and may reduce graft survival.
148 citations,
October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
101 citations,
May 2014 in “PLOS ONE” Women with PCOS have a higher chance of experiencing depression, anxiety, and sleep disorders.
90 citations,
May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
90 citations,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
71 citations,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
67 citations,
November 2019 in “Molecules” Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.
62 citations,
January 2009 in “Biochemistry” Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
55 citations,
January 2020 in “Advances in experimental medicine and biology” Vitamin D and its receptor may help prevent skin cancer.
48 citations,
May 2013 in “Canadian Medical Association Journal” Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.
40 citations,
September 2019 in “World journal of clinical cases” An elderly man's hair grew back after a treatment that transferred healthy gut bacteria.
40 citations,
January 2015 in “Indian Journal of Dermatology” Two new signs, 'signet ring vessels' and 'hidden hairs,' help tell apart scalp psoriasis and seborrheic dermatitis.
38 citations,
April 2017 in “PLOS Genetics” GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
31 citations,
July 2017 in “Stem cell investigation” Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.
29 citations,
April 2019 in “Acta neuropathologica communications” Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
21 citations,
February 2021 in “Frontiers in Endocrinology” Hormones affect prostate health and disease, with certain hormone imbalances linked to prostate cancer and benign prostatic hyperplasia.
19 citations,
January 2012 in “Biomolecules & Therapeutics” Grateloupia elliptica extract may help prevent hair loss and promote hair growth.
16 citations,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
16 citations,
January 2011 in “Indian Journal of Dermatology” Most patients with cicatricial alopecias face significant psychological and social challenges due to their hair loss.
15 citations,
April 2014 in “Experimental Dermatology” Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
14 citations,
May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.