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Off-pump heart surgery reduces complications without affecting survival rates compared to on-pump surgery.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Men taking 5-alpha reductase inhibitors for prostate issues may be less likely to experience severe COVID-19, but it doesn't prevent ICU admission or death.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Personalized medicine in dermatology uses molecular biomarkers to improve diagnosis and treatment but needs further advancements for practical use.

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

Current treatments for Alopecia Areata have mixed success, and there's a need for better, more accessible options and support for affected individuals.

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Antiandrogen therapy helps treat genetic hair loss.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.