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90-120 / 1000+ resultsresearch Immunohistochemical Localization of Basement Membrane Components During Hair Follicle Morphogenesis
research Expression of basement membrane components through morphological changes in the hair growth cycle
Fibronectin and other basement membrane components increase during hair growth and decrease during rest.
research Hair Follicle Proteoglycans.
research Human placental extract: a potential therapeutic in treating osteoarthritis
This review discusses the potential of human placental extract (HPE) in cartilage regenerative medicine for osteoarthritis, noting its significant anti-inflammatory and regenerative properties observed in vitro and in vivo studies, but reports no new clinical results.
research Biochemical and Ultrastructural Processing of [125I]Epidermal Growth Factor in Rat Epidermis and Hair Follicles: Accumulation of Nuclear Label
research Tumid Lupus Erythematosus and Systemic Lupus Erythematosus: A Report on Their Rare Coexistence
This case report presents a rare instance of coexistent tumid lupus erythematosus and systemic lupus erythematosus in a patient, with symptom improvement noted after hydroxychloroquine treatment.
research Disproportional signal of sexual dysfunction reports associated with finasteride use in young men with androgenetic alopecia: A pharmacovigilance analysis of VigiBase
This study found an association between finasteride use and increased reporting of suicidality and depression in young patients with androgenetic alopecia, potentially mediated by sexual dysfunction.
research Most Baricitinib Responders Achieved Full Scalp Hair Regrowth: Findings from Adult and Paediatric BRAVE-AA Trials
In this study, baricitinib, a JAK inhibitor, was found to significantly improve scalp hair regrowth in both adults and adolescents with severe alopecia areata, with many achieving nearly full regrowth by weeks 36 or 52.
research Hair removal options in darker skin types through laser innovation and energy-based modalities
This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.
research Baricitinib Achieved Complete/Near Complete Scalp Coverage in SALT Score ≤20 Responders: 52-Week Findings From BRAVE-AA Trials
In this analysis of the BRAVE-AA trials, a significant number of patients with severe alopecia areata treated with baricitinib reached complete or nearly complete scalp coverage (SALT score ≤10 or ≤5) over 52 weeks, particularly among those with less severe baseline characteristics.
research Litigation associated with 5-alpha-reductase-inhibitor use: A Canadian legal database review.
This study examined lawsuits in Canada involving 5α-reductase inhibitors, revealing that all cases related to persistent erectile dysfunction as a side effect in men treated for hair loss, but no judgments have been made yet against physicians or pharmaceutical companies.
research Correction to: An evaluation of the federal adverse events reporting system data on adverse effects of 5‑alpha reductase inhibitors
The correction states that the label change for Finasteride was in 2012, leading to more reports of side effects from non-healthcare people.
research Low Level Laser Treatment for Patterned Hair Loss: A Systematic Review
This review of low-level laser therapy for patterned hair loss found that red-spectrum light may be effective for hair growth, but larger case-controlled studies are needed to further support this conclusion.
research 017 Pharmacovigilance Analysis of Reports of Sexual Dysfunction Associated with Finasteride Use: Implications for the Post-Finasteride Syndrome
This study detected a significant association between finasteride use and sexual dysfunction, particularly in younger patients with alopecia, suggesting that indication and reporting stimulation may influence the observed signal.
research 222 Pharmacovigilance Analysis of Reports of Sexual Dysfunction Associated with Finasteride Use: Implications for the Post-Finasteride Syndrome
This study found significant signals of sexual dysfunction associated with finasteride use, particularly in younger patients treated for alopecia, though confounding factors may partly contribute to reported cases.
research Nutritional interventions in the treatment of Hashimoto’s disease: A systematic review
This integrative review analyzed nutritional interventions for Hashimoto’s thyroiditis (HT) and found that treatments such as micronutrient supplementation, anti-inflammatory diets, and lifestyle changes may help manage symptoms, though the effectiveness varied among studies.
research Association between Insulin Resistance and Hyperandrogenism among Women with PCOS in Pakistan
This study found that insulin resistance is common among Pakistani women with PCOS and is independently associated with increased hyperandrogenism, as indicated by correlations with testosterone levels and other androgenic measures.
research Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Phenolsulphotransferase: localization in kidney during human embryonic and fetal development
This study explored the localization of phenolsulphotransferase in human embryonic and fetal kidneys, finding distinct patterns of PST immunoreactivity in developing mesonephric and metanephric structures over time.
research The Transcriptional Regulator Prdm1 Is Essential for the Early Development of the Sensory Whisker Follicle and Is Linked to the Beta-Catenin First Dermal Signal
This study found that Prdm1 is crucial for whisker development in mice, affecting multiple signaling pathways and possibly playing a role in primates' evolutionary loss of vibrissae.
research Highlights from the Field of Pediatric Dermatology Research from the 2023 PeDRA Annual Conference
The conference highlighted new treatments and research in pediatric skin conditions, emphasizing collaboration and innovation.
research An Infant with Worsening Rash
This article presents a case study of a 3-month-old boy with a worsening rash initially diagnosed as impetigo, which did not improve with antibiotics and required further dermatological investigation.
research Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
This study found several microRNA-related genetic variants linked to epithelial ovarian cancer risk, with a notable association at the 17q21.31 region, suggesting potential new susceptibility genes.
research Proteoglycans and Associated Proteins of the Mammalian Hair Follicle
research Ultrastructure study of hair damage after ultraviolet irradiation
This study found that ultraviolet treatment for skin conditions such as vitiligo can damage hair, with psoralen plus ultraviolet A causing more follicle damage than narrow band ultraviolet B.
research Urological Oncology: Prostate Cancer
This article discusses the potential role of dutasteride in prostate cancer prevention, examining its effects on risk, but does not report new clinical findings.
research A Botanical Compound for the Treatment of Alopecia Areata and Chemotherapy-Induced Alopecia
This study reports promising preliminary trends in the safety and efficacy of a botanical drug candidate for pediatric alopecia areata, but conclusive results are not yet available.
research Exploring the “Thyroid–Skin Connection”: Concepts, Questions, and Clinical Relevance
This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
research Hair transplantation surgery - its current status.
This edition of the journal reviews major advances in hair restoration surgery, documenting increased popularity and technique improvements, but reports no new clinical results; the authors highlight ongoing challenges and call for balanced patient counseling.