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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Various treatments can improve post-acne scars, but results vary.

Heavily hunted wolves have higher stress and reproductive hormone levels.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Contact sensitizers like DCP and SADBE are the most effective treatments for alopecia areata.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.

Polycystic ovary syndrome (PCOS) was first described in 1721, officially diagnosed in the 1990s, and is now known to be partly genetic and linked to insulin resistance, with increased risk of cardiovascular disease and carbohydrate metabolism issues.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Medium-dose prednisolone pulse therapy is effective and safe for multifocal alopecia areata but not for more severe forms.

The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

Some patients developed hair loss after islet cell transplant possibly due to their immune-suppressing medications.

MR antagonists may improve skin health and wound healing, especially in aging.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

Androgen use may increase the risk of stroke, but more research is needed.

Eyelid cells share signaling components but differ in pathway activity.

The glucocorticoid receptor helps protect skin from tumors and other issues.