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Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Lower SHBG levels may increase the risk of PCOS.

Minoxidil promotes hair growth but stops working when discontinued.

TRH stimulates human hair growth and extends the hair growth phase.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Minoxidil absorbs poorly through skin, with low risk of side effects at 1-2% concentration.

Certain drugs that block specific enzymes can help treat prostate diseases.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Using neurohormones to control keratin can lead to new skin disease treatments.