4 citations
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June 2025 in “Cochrane Database of Systematic Reviews” This Cochrane review found no clear superiority among treatments for central serous chorioretinopathy, with low-dose photodynamic therapy, supplements, and eplerenone showing slightly higher probabilities of improving visual acuity, but evidence remains uncertain due to biases and small study sizes.
4 citations
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February 2022 in “Frontiers in molecular biosciences” This study revealed that chronic restraint stress in mice led to significant alterations in metabolic pathways and gene expression associated with hair growth inhibition, using metabolomics and transcriptomics analyses.
2 citations
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January 2005 in “The Japanese Journal of Veterinary Dermatology” In this study, Pomeranians with non-illness, generalized alopecia did not exhibit adrenal or pituitary abnormalities, suggesting a breed-specific hormonal pattern as a potential cause rather than a functional adrenal anomaly.
1 citations
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February 2025 in “Frontiers in Endocrinology” In this study, researchers observed that dietary vitamin D intake and light exposure play a crucial role in vitamin D metabolism in mice, suggesting similar importance for human health in maintaining optimal vitamin D levels.
January 2026 in “Frontiers in Medicine” This study found that acupuncture may reduce anxiety and depression in women with polycystic ovary syndrome, potentially through hormonal and neuroendocrine modulation, but further high-quality research is needed to confirm these findings.
January 2026 in “Annals of Dermatology” This study found high levels of anxiety, depression, and PTSD in dermatology patients one year after the February 6, 2023, earthquakes in Türkiye, with specific skin conditions like telogen effluvium and alopecia areata being more prevalent among those with psychological distress.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” In this review, researchers examined the concentration of cortisol in scalp hair of individuals with alopecia areata to explore its relationship with disease variables, as cortisol in hair can indicate chronic stress, which may impact alopecia areata pathogenesis.
In this systematic review, researchers observed that Toxoplasma gondii infection is associated with alterations in testosterone levels, generally increasing in humans but showing mixed effects in animals, highlighting a complex relationship that warrants further investigation.
September 2017 in “Journal of Investigative Dermatology” This study found that certain circulating miRNAs in skin and plasma may serve as potential biomarkers for distinguishing frontal fibrosing alopecia from control cases, highlighting the need for further validation in larger cohorts.
22 citations
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August 2015 in “Cochrane Database of Systematic Reviews” The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.
June 2026 in “Frontiers in Oncology” In this study, researchers analyzed adverse event reports from the FAERS database to identify safety concerns associated with ipilimumab in elderly patients, noting common issues like gastrointestinal events and new signals such as orchitis and alopecia areata, with timing influenced by body weight.
January 2026 in “Journal of Epidemiology” This cross-sectional study reported that adults with greater hair loss severity had significantly higher odds of hypertension, diabetes, and cardiometabolic multimorbidity, suggesting a possible link between hair loss and cardiometabolic health.
1 citations
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November 2025 in “Clinical Cosmetic and Investigational Dermatology” This Mendelian randomization study suggests possible bidirectional causal links between alopecia and sleep characteristics, but findings require cautious interpretation due to multiple testing, highlighting the need for further research to explore underlying mechanisms and broader applicability.
1 citations
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September 2016 in “Brain Behavior and Immunity” Hair cortisol levels can indicate stress and are affected by washing frequency, not cosmetic treatments.
May 2023 in “General and comparative endocrinology” This study found that hair cortisol concentrations in rhesus macaques were not significantly correlated with hair growth rate, suggesting that cortisol-mediated inhibition of hair growth does not explain higher cortisol levels within the non-stress range.
567 citations
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October 2007 in “Clinical and investigative medicine” This study described a new assay for measuring cortisol in hair and found it may serve as a useful biomarker for long-term cortisol exposure, correlating with 24-hour urine cortisol levels in non-obese subjects.
30 citations
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July 2023 in “Clinical Chemistry and Laboratory Medicine (CCLM)” In this study, researchers developed an LC-MS/MS method to accurately quantify cortisone and cortisol levels in human scalp hair, finding that concentrations decrease predictably along the hair shaft, which could assist in identifying abnormal glucocorticoid exposure.
2 citations
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January 2009 This study found that the hair cortisol measurement procedure was reliable, unaffected by the choice of tubes, and that hair cortisol concentration correlated moderately with the number of intense aggressions experienced.
157 citations
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June 2015 in “Psychoneuroendocrinology” This study observed that hair cortisol and cortisone concentrations were higher in older individuals and those with diabetes mellitus, highlighting their potential significance for assessing somatic health.
33 citations
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January 2017 in “Psychoneuroendocrinology” This study of Danish women found no evidence linking hair cortisol concentration to hair dyeing status or the frequency of hair washing.
23 citations
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January 2016 in “Brazilian Journal of Psychiatry” This study observed that drug-naïve first-episode psychosis patients had higher hair cortisol concentrations than healthy controls, and these concentrations correlated with the severity of psychopathology.
19 citations
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June 2020 in “General and comparative endocrinology” This study found that hair cortisol concentration is a promising stress indicator in cattle but not in pigs, where external factors and lower cortisol response may interfere with its validity.
October 2025 in “Journal of Veterinary Diagnostic Investigation” This study found that in domestic cats, black hair contained significantly higher cortisol concentrations than white hair, whereas ginger hair showed no significant difference compared to white hair. Additionally, a positive correlation was reported between hair cortisol levels and behavioral issues mentioned by cat owners.
122 citations
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October 2010 in “Clinica Chimica Acta” In this study, washing rhesus monkey hair with water or shampoo significantly reduced cortisol levels, suggesting potential underestimation of chronic stress hormone deposition in hair due to washing.
90 citations
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July 2014 in “Conservation Physiology” This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.
June 2020 in “Authorea (Authorea)” This study observed that pregnant women experienced an increase in hair cortisol concentrations, with primiparae having significantly higher levels in the last trimester compared to multiparae.
23 citations
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October 2008 in “Experimental and Clinical Endocrinology & Diabetes” This study found that measuring cortisol in human hair can reflect increased cortisol production for up to six months, with the highest concentration in hair closest to the scalp.
21 citations
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October 2009 in “Dermatology” This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.
13 citations
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October 2002 in “Journal of Biochemical and Biophysical Methods” This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.
9 citations
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February 2020 in “Stress” This study found that 6-year-old children experienced a significant increase in hair cortisol levels when entering third grade, which was linked to their level of inhibitory control.