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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.

Long COVID patients may have hormonal imbalances linked to their symptoms.

A neglected leprosy treatment led to rare scalp hair loss in an Indian woman, which improved with proper medication.

Feed restriction in sheep leads to finer wool fibers but may reduce wool quality.

Iron deficiency anemia can cause itching, which often improves with iron supplements.

Smoking is linked to more hair loss and premature graying compared to nonsmokers.

Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Diabetes can lead to blindness and skin problems, and managing blood sugar and blood pressure is crucial to prevent these complications.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Melanin density affects hair color, and this method can help in cosmetic assessments and diagnosing hair diseases.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.

miR-29 is a key factor that accelerates aging.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Neurosteroids show promise for treating epilepsy and more research is needed.

The document explains the diagnosis and characteristics of woolly hair nevus and alopecia neoplastica.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Fear of hair-related issues causes significant mental distress, especially in high-stress women.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Low-level laser therapy using near-infrared light may help heart conditions and promote healing by releasing nitric oxide.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.