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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Minoxidil sulfate stimulates hair growth.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Scientists created stem cells that can grow hair and skin.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

K16 can partially replace K14 but causes hair loss and skin issues.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.