9 citations,
March 2011 in “Current Pharmaceutical Biotechnology” Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
30 citations,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
40 citations,
June 2013 in “Molecular Pharmaceutics” The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
235 citations,
January 2011 in “Journal of Clinical Investigation” Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
67 citations,
December 2009 in “Stem Cells” β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.
240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
6 citations,
December 2019 in “BMC Complementary and Alternative Medicine” Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.
6 citations,
July 2013 in “Molecular Imaging” The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
39 citations,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
August 2024 in “Applied Sciences” Plant extracts may help prevent or reverse hair graying.
49 citations,
February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
2 citations,
December 2022 in “Journal of toxicologic pathology” Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
25 citations,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
77 citations,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
97 citations,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
74 citations,
September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
2 citations,
May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
21 citations,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
23 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
12 citations,
January 2009 in “Stembook” Improved understanding of stem cell mechanisms can enhance skin tissue engineering.
2 citations,
January 2016 in “Springer eBooks” Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.