3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
January 2007 in “동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine” This study suggests that acetone extracts and certain fractions of Drynariae Rhizomas may support hair growth when applied topically in C57BL/6N mice models, indicating potential use for treating alopecia areata.
April 2025 in “Tropical Journal of Natural Product Research” This study reports that a nanoemulsion was successfully formulated to deliver Moringa oleifera seed oil, which contains oleic acid and other fatty acids, and may serve as a promising dosage form for hair growth treatments.
35 citations
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January 2018 in “Skin pharmacology and physiology” This study found that nanoemulsion formulations with oleic acid or eucalyptol significantly enhanced the delivery and retention of caffeine through hair follicles and surrounding skin regions.
9 citations
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January 2017 in “Food & Nutrition Research” In this study, rice bran mineral extract increased expression of anagen-related proteins and decreased inflammatory markers in human dermal papilla cells, suggesting potential for hair growth enhancement and prevention of hair loss.
February 2026 in “Cosmetics” This review highlights that Trigonella foenum-graecum L. (fenugreek) shows promise as a versatile plant-based ingredient in cosmetics due to its phytochemicals, which offer benefits for skin and hair care, although further research is necessary for robust validation.
3 citations
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July 2015 in “International journal of pharmacology” In this study, Natural Plant Extracts (NPE) promoted hair growth in mice by stimulating anagen growth and upregulating relevant gene expression, compared to controls with saline.
March 2024 in “Molecules/Molecules online/Molecules annual” This study optimized the extraction process of bear grease through enzymatic hydrolysis and found that it was rich in unsaturated fatty acids, enhancing its hair growth-promoting properties in mice compared to traditional methods.
19 citations
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December 2013 in “European journal of pharmaceutics and biopharmaceutics” This study found that encapsulated Garcinia mangostana Linn extract in a cream base penetrated more deeply and homogeneously into porcine ear skin compared to other formulations.
November 2025 in “Frontiers in Pharmacology” This study observed that both in vitro and in vivo research demonstrated rice bran extract can significantly enhance collagen and elastin synthesis, reduce water loss, and improve skin quality and elasticity, highlighting its potential as a sustainable cosmetic ingredient.
7 citations
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January 2015 in “Biological & Pharmaceutical Bulletin” This study found that a 16-week dermal application of rice bran extract significantly increased hair density and diameter in male androgenic alopecia patients without causing adverse reactions.
January 2024 in “Journal of Medicinal Food” This study found that Nephelium lappaceum extract restored hair growth more effectively than finasteride in mice with testosterone-inhibited hair growth, suggesting its potential as a nutraceutical for hair growth.
February 2024 in “Archiv EuroMedica” This review suggests that annurca apple extract, rich in polyphenols, may be a promising alternative for treating baldness, though further research is needed to clearly assess its effectiveness compared to existing treatments.
September 2016 in “Journal of Dermatological Science” This study found that P. cornucopiae extract showed antioxidant and protective effects on human skin fibroblasts, suggesting its potential as an antiaging agent by preventing oxidative stress-induced collagen breakdown.
July 2024 in “Natural Product Research” Nk-EE may help treat hair loss by promoting hair growth and preventing hair follicle damage.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights recent advancements in the formulation of herbal hair creams, focusing on the use of natural ingredients like kidney bean extract and aloe vera, eco-friendly extraction methods, and modern pharmaceutical technologies to create effective and safe products for hair care.
May 2026 in “Riset Informasi Kesehatan” This experimental study evaluated shampoo formulations with varying concentrations of candlenut oil, concluding that the 12% formulation (Formula 2) demonstrated optimal physical characteristics and quality standards, with acceptable pH and viscosity but reduced foam stability at higher oil concentrations.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that a mixed extract of N. jatamansi, O. basilicum, and C. sativus, particularly when extracted via steaming and ultrasonic methods, increased antioxidant content, stimulated melanin production for black hair, and promoted hair growth in mouse models, while maintaining high cell viability.
This study suggests that Tenebrio molitor larvae extract may promote hair growth and prevent hair loss by enhancing cell proliferation and protecting against cytotoxicity in laboratory settings.
10 citations
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March 2010 in “Journal of Food Biochemistry” This study found that Sithong-bao seed coat extract, with high phenolic content, exhibited the strongest antioxidant properties among certain Thai tamarind cultivars, suggesting potential for nutraceutical development.
June 2023 in “Journal of Ayurvedic and herbal medicine” This review article highlights the potential health benefits and pharmaceutical components of pumpkin seeds, which contain proteins, antioxidants, and essential nutrients, and discusses their traditional medicinal uses and emerging applications in the food industry.
February 2024 in “PloS one” This study found that certain nutraceuticals did not interfere with tamoxifen's inhibition of estrogen in breast cancer cells and may enhance its effects, suggesting potential as an adjuvant therapy for hair loss in patients undergoing endocrine therapy.
2 citations
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February 2021 in “IOP Conference Series Earth and Environmental Science” This study identified that Mangkokan leaf extracts contain active compounds such as alkaloids, flavonoids, steroids, tannins, phenols, and saponins, using different solvents and FTIR analysis.
January 2019 in “Proceedings for Annual Meeting of The Japanese Pharmacological Society” In this study, injecting Nε-(carboxymethyl) lysine into skin tissue weakened hair shaft and follicle formation, likely by inhibiting cell proliferation and migration needed for hair follicle morphogenesis.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the formulation and evaluation of herbal hair creams using ingredients like kidney beans, aloe vera, and vitamin E, highlighting recent advances such as eco-friendly extraction techniques and computer-aided optimization to enhance application ease, shelf life, and effectiveness in maintaining a healthy scalp.
January 2020 in “대한미용학회지” This review discusses various natural substances used in scalp improvement cosmetics and reports their potential benefits, without providing new clinical results, and suggests more comprehensive studies are needed.
3 citations
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July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
January 2026 in “Lumbung Farmasi Jurnal Ilmu Kefarmasian” This study found that a topical emulsion containing purified extracts of sidr leaves and roasted candlenut seeds significantly increased hair growth compared to the base and 2% minoxidil, potentially through their antioxidant and anti-inflammatory properties.
May 2023 in “Pharma innovation” This review discusses PUFA-rich oil seeds and microencapsulation techniques but reports no new clinical results; the authors highlight microencapsulation as a promising method to protect PUFAs from oxidation.
December 2023 in “International Journal of Health and Pharmaceutical” This study found that a mixture of 80% coconut oil and 20% candlenut oil effectively stimulated hair development in Wistar rats, which may be attributed to the high lauric acid content in coconut oil.