54 citations
,
May 2018 in “International journal of risk & safety in medicine” This study observed enduring sexual dysfunction reported in 300 cases globally following the use of SSRIs, finasteride, and isotretinoin, with common symptoms like genital anaesthesia and loss of libido.
54 citations
,
April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” This review discusses 46,XY disorders of sex development caused by defects in androgen production and highlights the need for long-term care from experienced multidisciplinary teams, but it reports no new clinical findings.
46 citations
,
August 2022 in “Animals” This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.
45 citations
,
January 2012 in “Experimental Dermatology” This study reveals that human hair follicles transition between active and dormant states stochastically, challenging the idea of a cyclical automaton controlling hair growth.
37 citations
,
January 1979 in “Archives of Dermatology” This case report suggests that PUVA treatment may have played a role in triggering systemic lupus erythematosus in a 23-year-old woman with psoriasis.
35 citations
,
October 2021 in “Journal of the European Academy of Dermatology and Venereology” This report describes two cases where a viral vector COVID-19 vaccine was associated with the recurrence of cutaneous lymphoma conditions that had been in remission.
35 citations
,
July 2018 in “BMJ Open” This study found that patients with atopic dermatitis have a higher risk of developing keloid, suggesting it may be an independent risk factor for keloid formation.
35 citations
,
June 2011 in “British Journal of Dermatology” This study found that in an Italian population, the HLA-DQB1*03 allele was associated with increased susceptibility to alopecia areata, particularly in cases with more than 50% hair loss.
35 citations
,
January 2006 in “Dermatology Online Journal” This study observed that finasteride treatment induced mild improvement in androgenetic alopecia in one male patient while stabilizing the condition in another, but lipedematous scalp remained unchanged.
31 citations
,
January 2016 in “Skin Appendage Disorders” This study observed two cases of frontal fibrosing alopecia developing on preexisting vitiligo, suggesting a potential causal link between the two conditions.
30 citations
,
April 2017 in “European Journal of Cell Biology” This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.
29 citations
,
February 1987 in “General and comparative endocrinology” This study found that in male badgers, seasonal molting and hair growth are influenced by cycles of plasma testosterone and thyroxine, with hormones affecting the timing and progression of these processes.
28 citations
,
February 2010 in “Experimental Dermatology” This study concluded that the frizzy mutation in mice is linked to a T to A transversion in Prss8 and is orthologous to the 'hairless' mutation in rats.
27 citations
,
July 1997 in “PubMed” This study suggests that the harlequin ichthyosis mouse model closely resembles human type 2 harlequin ichthyosis, indicating its potential as a useful model for studying the human condition.
26 citations
,
September 2010 in “Experimental Dermatology” In this study, researchers identified two independent genetic variants near the androgen receptor gene strongly associated with androgenetic alopecia in men.
26 citations
,
February 1998 in “Chemico-Biological Interactions” This review discusses recent molecular biology advances in the human phenol sulfotransferase gene family and reports no new results; the authors highlight its relevance for studies of endogenous and xenobiotic metabolism.
26 citations
,
September 1990 in “Ophthalmology” This case study found that a 7-year-old girl's crystalline cataract had sulfur-containing amino acids likely cystine, and was associated with abnormal hair conditions.
25 citations
,
October 2000 in “Gene” This study found that Foxn1-like genes in fish and mice are functionally equivalent in activating hair keratin genes, whereas changes in the cephalochordate Foxn1-like gene result in inactivity.
25 citations
,
September 1995 in “Biochemistry and Cell Biology” This study found that high levels of human cytokeratin 16 expression in transgenic mice lead to skin lesions and altered keratinocyte structure, suggesting potential implications for human skin disorders and wound healing.
22 citations
,
June 2004 in “Journal of The European Academy of Dermatology and Venereology” This case report identifies a novel association between Graham Little–Piccardi–Lassueur syndrome and complete androgen insensitivity syndrome, suggesting the influence of androgens in the alopecias accompanying the former may be limited.
21 citations
,
February 2012 in “Journal of the European Academy of Dermatology and Venereology” This study found that late-onset alopecia areata is more common in women and tends to present with milder symptoms, with some patients achieving complete hair regrowth in mild cases.
20 citations
,
May 2000 in “Journal of The American Academy of Dermatology” This report suggests that orf infections in Brussels often occur after the Islamic Feast of Sacrifice due to the ritual sheep sacrifice, affecting both men and women handling the animals.
19 citations
,
May 2006 in “Clinical and Experimental Dermatology” This study identified a novel insertion mutation in the hairless gene that may contribute to the development of congenital atrichia with papular lesions in a Pakistani family.
18 citations
,
October 2017 in “PLOS ONE” This study found that in Pomeranians with Alopecia X, key genes in the Wnt and Shh signaling pathways and stem cell markers are downregulated, which may explain the absence of anagen hair follicles.
17 citations
,
October 1997 in “Australian Journal of Agricultural Research” This study observed that nutritional stress is likely responsible for changes in Merino sheep follicle morphology in Mediterranean environments, affecting staple strength and possibly requiring targeted management strategies.
16 citations
,
January 2012 in “Indian Journal of Endocrinology and Metabolism” This case series describes six women with both PCOS and Graves' disease, suggesting a possible shared underlying cause for their co-occurrence.
15 citations
,
February 1999 in “The anatomical record” This study found that defective cross-linking in hair cuticles is observable in a minority of mouse hair mutants, suggesting different proteins are involved in cross-linking across cell types.
15 citations
,
August 1991 in “Histochemistry and Cell Biology” Enhancing Factor is found in growing tissues like young mouse intestines and skin but not in adults.
15 citations
,
January 1981 in “Neonatology” This study observed that changes in amino acid levels in milk correlate with developmental events in pouch young marsupials, notably around hair follicle development and homeothermy onset.
12 citations
,
May 2024 in “International Journal of Nanomedicine” This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.