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Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Scientists identified a unique type of human skin stem cell that could help with tissue repair.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Mothers and newborns with dental fillings have higher mercury in their hair, but adding fillings during pregnancy doesn't raise mercury levels further.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Oestrogens are key for bone growth during puberty in both boys and girls.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Stem cell self-renewal is complex and needs more research for full understanding.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Voriconazole can cause serious side effects, especially in long-term use.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

SHBG may be a useful early indicator and treatment target for PCOS.