54 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.
38 citations
,
August 1999 in “New England journal of medicine/The New England journal of medicine” This letter discusses observations of indinavir's effects on skin, likening them to those of retinoids, but does not present new clinical findings.
28 citations
,
December 1997 in “Journal of Biological Chemistry” This study found that the hHa1-t protein variant, caused by a genetic polymorphism in the hHa1 gene, forms functional keratin filaments despite lacking a complete nonhelical tail domain, explaining the absence of a pathological hair phenotype.
20 citations
,
August 2022 in “Frontiers in Immunology” This review discusses the role of fibroblasts in treating diabetic complications and wound healing, highlighting their potential as immunomodulatory factors but provides no new clinical results.
18 citations
,
July 2022 in “Frontiers in Immunology” This review discusses the potential impact of volatile organic compound exposure on the onset and progression of autoimmune diseases and reports no new experimental findings.
7 citations
,
May 2022 in “Frontiers in Cell and Developmental Biology” This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.
6 citations
,
July 2021 in “Bulletin of the National Research Centre/Bulletin of the National Research Center” This review discusses the transmission and immune response of SARS-CoV-2 and highlights ongoing research for developing vaccines and antiviral treatments, but it presents no new clinical findings.
5 citations
,
June 2024 in “Free Radical Biology and Medicine” This review highlights that current in vitro models often fail to replicate the physiological oxygen levels experienced by different skin cell types, which could affect redox states and functions, potentially accelerating skin aging.
5 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.
4 citations
,
June 2023 in “Journal of developmental biology” In this study, researchers propose that different vertebrate skin appendages, such as hair, feathers, and scales, evolved in parallel from a shared ancestral cell structure associated with teeth, dating back approximately 420 million years ago.
4 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
3 citations
,
September 2023 in “Genes” This study analyzed the molecular evolution and functional divergence of the Dkk gene family, finding accelerated evolution in Aves and Reptilia and identifying functional differences that may impact hair follicle development via Wnt signaling inhibition.
3 citations
,
December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal” This study found that compound 3 derived from aza-bicyclo-carboxylic acid may exert a cardioprotective effect by reducing infarction area in myocardial ischemia-reperfusion injury, potentially involving A1-adenosine receptor activation and changes in cAMP levels.
1 citations
,
January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
1 citations
,
March 2022 in “IntechOpen eBooks” This chapter discusses various aspects of collagen, proposing "extended collagen carential disease" as a new concept tied to nutritional deficiencies, notably Vitamin C's role in maintaining collagen health.
1 citations
,
March 2018 in “F1000Research” This study found that diazepam has an exaggerated effect on GABAergic inhibitory tone in diabetic neuropathy mouse models, likely due to upregulated neurosteroidogenic enzymes responding to mitochondrial dysfunction.
May 2026 in “Journal of Clinical Medicine” In this study, post-COVID-19 patients showed substantial multisystem symptoms six to eight months after infection compared to controls, with a higher burden in non-respiratory areas like fatigue and neurocognitive issues, despite respiratory symptoms largely resolving.
April 2026 in “Veterinary Medicine and Science” In this case report, authors described a pet golden hamster with a confirmed adrenocortical adenocarcinoma, where laboratory testing and diagnostic imaging enabled antemortem diagnosis, despite the species' rarity for these procedures.
January 2026 in “Preprints.org” This review explores current knowledge on fibroblast lineage specification and its impact on scar-free wound healing, noting that early fetal skin fibroblasts support regeneration, while later developmental shifts lead to fibrosis, highlighting potential strategies to reprogram adult fibroblasts for regenerative repair.
January 2025 in “Health engineering.” This study reviews the role of skin stem cells in aging and explores how organoids, as opposed to traditional methods, can advance research into aging skin and regenerative therapies.
This study explored social perceptions of men with androgenetic alopecia, finding that increased hair loss was associated with perceptions of being older, less attractive, smaller, and less masculine, but more family-oriented and socially agreeable, highlighting how hair loss influences first impressions.
November 2023 in “International journal of reproduction, contraception, obstetrics and gynecology” This review discusses the hypotheses surrounding the developmental origins of polycystic ovary syndrome, particularly the role of prenatal androgen exposure, and reports no new experimental results.
September 2023 in “World Rabbit Science” In this study using Angora rabbits, researchers found that the FRZB gene inhibits hair follicle development by modulating the Wnt/β-catenin signaling pathway, affecting the expression of various genes related to this pathway and altering cell proliferation and apoptosis.
July 2023 in “Journal of Clinical Medicine” This paper identifies challenges in diagnosing alopecia variants, emphasizing the importance of pathologists understanding hair follicle histology, biopsy types, and collaborating with dermatologists to improve diagnostic accuracy.
May 2023 in “Frontiers in Immunology” This article discusses the role of regulatory T cells in alopecia areata, where their deficiency in hair follicles may lead to impaired local immunity and suggests potential therapies like CAR-T reg cells and low-dose IL-2 to alleviate autoimmunity and promote hair regeneration in affected individuals.
96 citations
,
September 2021 in “International Journal of Molecular Sciences” This review highlights recent advances in chitosan-based nanoparticles (CS NPs) for drug delivery, discussing their modifications, preparation methods, production with organic and inorganic materials, and their latest implementations in the field, emphasizing the role of CS NPs in improving drug transport and release properties.
6 citations
,
November 2016 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This survey found support among BAAPS members for using procedure-specific consent forms to improve clarity and consistency in patient information for aesthetic procedures.
1 citations
,
December 1997 in “The British Journal of Psychiatry” This document outlines the indications, dosing, side effects, and contraindications for Epilim in epilepsy treatment, with no new research findings presented.
115 citations
,
March 2019 in “Nature Communications” This study identified significant genetic associations with frontal fibrosing alopecia at four genomic loci, suggesting it is a genetically predisposed immuno-inflammatory disorder influenced by the HLA-B*07: 02 allele.
65 citations
,
March 2016 in “Lasers in Medical Science” This review found that many low-level light therapy studies report beneficial effects but often fail to provide adequate measurement details, affecting the reliability and repeatability of the research.