December 2012 in “Bulletin of Egyptian Society for Physiological Sciences” This study found that topical application of copper (II) albumin complex improved healing signs in rats with full thickness thermal burns, enhancing antioxidant, anti-inflammatory, and pain modulating effects.
2 citations
,
April 2025 in “Biomedicine & Pharmacotherapy” This research reports that copper-quercetin complexes show strong potential in antioxidation and cancer therapy, while their effects on specific cell death pathways warrant further investigation.
1 citations
,
May 2016 in “Marmara Pharmaceutical Journal” This study determined the stability constants of finasteride complexes with cobalt, zinc, cadmium, and copper, which may inform analyses of blood samples.
165 citations
,
January 2008 in “Journal of biomaterials science. Polymer ed.” This review outlines the various processes activated by the peptide GHK-Cu in tissue remodeling and reports improvements in skin and wound healing but notes a need for further study to fully understand these mechanisms.
This article reviews the potential benefits of GHK-Cu, EAA, and water-soluble propolis for wound healing, skin tightening, and anti-aging effects, but reports no new clinical results.
January 2017 in “Springer eBooks” Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.
33 citations
,
January 1996 in “CRC Press eBooks” This article reviews various models used in dermatopharmacology research, exploring their applications in studying skin conditions and hair growth, but reports no new findings.
June 2026 in “Journal of Advances in Biology & Biotechnology” In this study conducted at the Veterinary Clinical Complex in Bikaner, Rajasthan, researchers found that among 240 canine dermatitis cases, 25 dogs had demodicosis, characterized by various hematological and serum biochemical changes, and distinctive histopathological alterations in skin samples.
12 citations
,
June 2022 in “International Journal of Molecular Sciences” In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.
26 citations
,
April 2021 in “Materials & Design” This study found that composite chitosan nanofibers containing luminescent europium complexes can sensitively detect Cu2+ concentrations as low as 10 μmol/L, making them suitable for use in biological systems.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.
11 citations
,
February 2018 in “Amino acids” This study found that homocysteine-keratin accumulation in human hair increases towards the tips, linked to copper/iron-catalyzed demethylation of methionine, and may contribute to keratin damage.
1 citations
,
January 2025 in “Molecules” This review reported that while glycyl-L-histidyl-L-lysine tripeptide copper complex (GHK–Cu) has limited skin permeation when used alone, liposomes may enhance its absorption, but there is limited research on this aspect, highlighting a need for further studies.
65 citations
,
March 2017 in “Experimental Dermatology” This review discusses the genetic and biological factors influencing hair curliness, revealing strong links to specific protein variations, and reports no new clinical results.
23 citations
,
January 2019 in “Journal of wildlife diseases” This study found that a significant number of boreal woodland caribou in NE British Columbia showed symptoms of trace mineral deficiencies and exposure to various pathogens, with substantial winter tick infestations affecting a majority of individuals.
19 citations
,
July 2004 in “Journal of Medical Primatology” In this study, zinc toxicosis in infant baboons was attributed to excessive environmental exposure, highlighting the importance of cage design in captivity and potential use of baboons as a developmental model.
10 citations
,
January 2025 in “Biomaterials Science” This study found that a multifunctional hydrogel dressing enriched with Cu-MOF and tannic acid significantly improved full-thickness wound healing in rats, reducing the wound area to only 1.6% and promoting re-epithelialization, neovascularization, and hair follicle formation.
2 citations
,
October 2018 in “The journal of pediatrics/The Journal of pediatrics” This case report identified a 4-month-old boy with Menkes disease, a neurodegenerative disorder of copper metabolism, noting symptoms like recurrent seizures, developmental delay, and specific physical characteristics, confirmed by genetic sequencing showing a pathogenic ATP7A mutation and low serum copper and ceruloplasmin levels.
April 2024 in “Materials today bio” In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
December 2015 in “Basrah Journal of veterinary Research” In this study, researchers found that most buffaloes in Basrah, Iraq, suffered mineral deficiencies, especially in zinc, cobalt, copper, and sulfur, with outdoor grazing buffaloes displaying more severe deficiencies than those kept indoors.
August 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This source provides supplementary materials for the Carnivore Follicular Integrity Framework, a theoretical model proposing that animal-based diets may support hair follicle stability through several biological mechanisms. The materials include definitions, nutrient tables, and mechanistic notes but do not report empirical results.
July 2026 in “World Journal of Advanced Research and Reviews” In this case report, a 49-year-old heavy smoker experienced scalp necrosis after hair transplantation, but wound closure was achieved within two weeks using a treatment combining topical agents and photobiomodulation; the potential role of photobiomodulation needs further study.
36 citations
,
September 2019 in “Journal of Herbal Medicine” This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.
2 citations
,
July 1998 in “Dermatologic Clinics” This review examines the differences in dermatology practices between Europe and North America, noting that European dermatologists often prioritize evaluating patients' psychosocial factors and utilize nondrug treatments, unlike their North American counterparts.
6 citations
,
July 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that a composition containing mannose-6-phosphate significantly reduced the total skin pore area by 24% in women after 56 days and by 30.2% in men after 7 days, suggesting its effectiveness in improving pore appearance by targeting dermal and epidermal modifications.
1 citations
,
September 2020 in “The Indian journal of veterinary sciences and biotechnology” This study observed that mange-infested camels showed significant hematological and biochemical changes, indicating hepatocellular and renal damage as well as increased stress compared to healthy camels.
8 citations
,
November 2023 in “Frontiers in Bioengineering and Biotechnology” This article reviews recent developments in microneedles combining metallic elements and herbal compounds for wound healing, highlighting their benefits such as enhanced therapeutic efficacy and reduced toxicity, and offering a reference for future advancements in this technology.
May 2014 in “The Journal of Alternative and Complementary Medicine” Higher levels of chromium, selenium, and copper in hair are linked to increased insulin resistance in visceral-obese adults.
3 citations
,
May 2014 in “InTech eBooks” This review discusses the genetic and androgen-related factors in androgenetic alopecia, highlighting a specific polymorphism in the AR protein associated with male pattern hair loss, and reports no new clinical results.
January 2013 in “Food science and technology research” This study reported that green tea extract may promote the excretion of copper into the hair in mice.