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Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Diet changes can protect against harmful environmental effects on fetal development.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Stem cell self-renewal is complex and needs more research for full understanding.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

New treatments targeting specific genes show promise for treating keratin disorders.

Melatonin helps regulate hair growth and protects the hair follicle from stress.