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    Glossary Cooling Methods

    techniques to lower scalp temperature during chemotherapy to prevent hair loss

    Cooling methods refer to techniques used to lower the temperature of the scalp during chemotherapy to reduce the risk of hair loss, a condition known as chemotherapy-induced alopecia. These methods typically involve the use of cold caps or scalp cooling systems that constrict blood vessels, thereby limiting the amount of chemotherapy drugs that reach the hair follicles. This can help preserve hair and improve the quality of life for patients undergoing treatment.

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    1. Scalp Cooling Methods for Chemotherapy-Induced Hair Loss: A Comprehensive Review from Traditional Practices to Modern Innovations 2025
    2. Hair loss as a consequence of cancer chemotherapy – physical methods of prevention. A review of the literature Wspolczesna Onkologia-Contemporary Oncology · 2011 · 3 citations
    3. Theoretical considerations in laser hair removal Dermatologic Clinics · 1999 · 150 citations
    4. A clinical overview of hair removal using lasers and light sources Dermatologic Clinics · 1999 · 73 citations
    5. Long pulsed Nd: YAG laser with inbuilt cool sapphire tip for long term hair reduction on type- IV and V skin: A prospective analysis of 200 patients Indian journal of dermatology, venereology, and leprology · 2010 · 10 citations
    6. Cutaneous Side Effects of Chemotherapy and Radiotherapy 2016 · 2 citations
    7. Alopecia in oncology: the practical significance of fundamental research Sibirskij onkologičeskij žurnal · 2023
    8. A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention Oncologist · 2017 · 38 citations
    9. Efficacy of Scalp Cooling in the Prevention of Chemotherapy Induced Alopecia Among Breast Cancer Patients Sciential - McMaster Undergraduate Science Journal · 2023 · 1 citations
    10. Contact cooling of the skin Physics in Medicine and Biology · 1999 · 92 citations
    11. Presentation, impact and prevention of chemotherapy-induced hair loss: scalp cooling potentials and limitations Expert review of dermatology · 2011 · 62 citations
    12. Clinical aspects of scalp cooling in chemotherapy induced alopecia 2020 · 1 citations
    13. Formulation and characterisation of resveratrol-loaded nanostructured lipid carriers for use in combination with scalp cooling therapy to mitigate chemotherapy-induced follicular cytotoxicity and hair loss Journal of Drug Delivery Science and Technology · 2025
    14. Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming? Current Oncology · 2023 · 4 citations
    15. Non-pharmacological therapies in the treatment of chemotherapy-induced alopecia – a literature review Journal of Education Health and Sport · 2025
    16. Cryopreservation of Hair-Follicle Associated Pluripotent (HAP) Stem Cells Maintains Differentiation and Hair-Growth Potential Advances in experimental medicine and biology · 2016 · 4 citations
    17. Scalp cooling and chemotherapy-induced alopecia: Evaluating cost-effectiveness and insurance coverage Dermatology Online Journal · 2026
    18. Hair removal using the long-pulsed ruby laser Dermatologic Clinics · 1999 · 4 citations
    19. Efficacy of Scalp Cooling System Versus Chemical Cooling Cap in Preventing Chemotherapy-induced Alopecia in Breast Cancer (COHAIR Study): a prospective randomized trial The Breast · 2026
    20. DRUGS AND DEVICES IN PREVENTION AND TREATMENT OF CHEMOTHERAPY-INDUCED ALOPECIA: WHEN AND HOW SHOULD BE EMPLOYED 2019
    21. Patient-reported outcome assessment and objective evaluation of chemotherapy-induced alopecia European journal of oncology nursing · 2018 · 8 citations
    22. Optimizing hair care products and practices for Black patients with breast cancer: One size does not fit all JAAD reviews. · 2025 · 1 citations
    23. Hair Disorders Associated with Anticancer Agents 2013
    24. Scalp cooling in the prevention of anthracycline-induced alopecia European journal of cancer · 2001 · 4 citations
    25. No prevention of radiotherapy-induced alopecia by scalp cooling Radiotherapy and oncology · 2015 · 8 citations
    26. Efficacy and tolerability of two scalp cooling systems for the prevention of alopecia associated with docetaxel treatment Supportive Care in Cancer · 2013 · 52 citations
    27. Scalp cooling versus standard cold-cap in preventing chemotherapy-induced alopecia in patients with localized breast cancer: ICELAND protocol, a randomized controlled trial and economic evaluation PLoS ONE · 2026
    28. Scalp cooling to prevent chemotherapy-induced alopecia 2020 · 17 citations
    29. The efficacy of scalp-cooling system for the prevention of chemotherapy-induced hair loss in metastatic breast cancer patients treated with eribulin Annals of oncology · 2018
    30. Transnasal cooling: A Pandora’s box of transnasal patho-physiology Medical Hypotheses · 2011 · 3 citations