June 2026 in “International Journal of Drug Delivery Technology” This review explores the potential of herbal therapies and modern delivery methods for managing premature hair greying, highlighting promising plant-based treatments and emphasizing the need for clinical trials to validate their effectiveness.
April 2026 in “International Journal of Drug Delivery Technology” This study discusses advancements in nanotechnology and theranostic dressings, which may significantly improve chronic wound care by effectively targeting biofilms and enabling real-time monitoring, although obstacles to broad applicability and sustainability remain.
January 2026 in “Frontiers in Materials” This review discusses the potential of metal organic frameworks for drug delivery in wound treatment, highlighting their unique properties and recent research advancements, but reports no new clinical results.
December 2025 in “Frontiers in Nutrition” This review suggests that although hydrolyzed collagen peptides with certain supplements may improve skin elasticity and joint function, evidence for collagen's anti-aging and regenerative benefits remains inconsistent.
March 2025 in “Frontiers in Pharmacology” This study developed a hydrogel dressing incorporating angelica polysaccharides, demonstrating enhanced wound healing properties in a mouse model by promoting rapid hemostasis, tissue healing, and new blood vessel formation compared to Tegaderm™ film.
223 citations
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October 2020 in “Microsystems & Nanoengineering” This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.
183 citations
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January 1987 in “British Journal of Anaesthesia” This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.
87 citations
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March 2020 in “Australian Dental Journal” This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
7 citations
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March 2023 in “Antioxidants” This study confirmed the antioxidant role of rosemary, suggesting its potential use in treating inflammatory and infectious skin conditions, but emphasizes that more large-scale controlled trials are necessary to fully understand its clinical impact.
June 2011 in “CRC Press eBooks” Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.
5 citations
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January 2013 in “Otorhinolaryngology clinics : an international journal” This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.
25 citations
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July 2014 in “Hong Kong medical journal” This review discusses potential associations between Helicobacter pylori infection and various skin diseases but reports no new clinical findings; more research is needed to clarify these links.
This study developed a bioresponsive hydrogel combining basic fibroblast growth factor and N-acetylcysteine, which significantly improved diabetic wound healing by enhancing re-epithelialization, collagen deposition, hair follicle regeneration, and neovascularization in response to oxidative stress.
2 citations
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February 2025 in “Journal of Nanobiotechnology” In this study, metal-organic frameworks modified with stearic acid were used to deliver cardamonin to hair follicles, significantly promoting hair growth and cell proliferation in testosterone-challenged mice, suggesting potential benefits for androgenic alopecia treatment.
14 citations
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February 2024 in “Pharmaceutics” This review highlights that while nanoparticle-loaded dissolving microneedles have considerable promise for enhancing transdermal drug delivery, progress is delayed by insufficient understanding of their in vivo behavior, which the authors emphasize as crucial for advancing clinical applications.
2 citations
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December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
1 citations
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July 2025 in “MedComm – Biomaterials and Applications” This review discusses the potential of microneedles in cancer diagnosis and treatment, highlighting advances and ongoing clinical trials, but reports no new results; it emphasizes the minimally invasive nature of this technology.
3 citations
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July 2025 in “Gels” This review explores how recombinant protein hydrogels, employing molecular engineering and crosslinking strategies, offer advanced applications in regenerative medicine by mimicking extracellular matrix dynamics and providing enhanced mechanical, environmental, and biological properties.
73 citations
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February 2023 in “Polymers” This review discusses the unique properties, design, and fabrication of peptide hydrogels for biomedical applications, focusing on advances in drug delivery, gene therapy, and regenerative medicine; it reports no new clinical results.
18 citations
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February 2025 in “Macromolecular Rapid Communications” In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.
November 2024 in “International Journal of Molecular Sciences” This study developed caffeine-loaded nanoparticles coated with ultradeformable liposomes for better hair follicle delivery, showing non-cytotoxicity and potential to reduce oxidative stress in DHT-damaged cells, suggesting an alternative treatment for androgenetic alopecia.
65 citations
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March 2022 in “Molecules” This study examines the role of nanotechnology in cosmetics, highlighting its benefits in improving ingredient solubility and stability, but also noting challenges such as cost, shelf life, and safety concerns, along with regulatory complexities, particularly in harmonizing global legislation.
8 citations
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November 2019 in “International Journal of Pharmaceutics” This work explores using a liquid crystalline phase to stabilize benzoyl peroxide nanosuspensions, suggesting a promising method to potentially reduce the side effects of acne treatments.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
March 2025 in “Advanced Science” In this study, bioengineered hair germ microspheres made from HME hydrogels promoted hair follicle regeneration in vivo, suggesting a promising approach for hair loss treatment.
18 citations
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September 2021 in “Colloids and surfaces. B, Biointerfaces” This study explored the development of polymeric nanoparticles for topical spironolactone delivery, finding that larger nanoparticles (180 nm) enhanced drug targeting to hair follicles significantly more than smaller ones or non-nanoparticle formulations, offering promise for safer acne and alopecia treatments.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.
Intermittent fasting slows hair growth by damaging hair follicle cells.
June 2025 in “Journal of Drug Delivery Science and Technology” A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.