43 citations,
May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
43 citations,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
30 citations,
February 2003 in “Annals of Neurology” Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
28 citations,
June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
24 citations,
January 2018 in “Development” Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.
16 citations,
November 2020 in “PLOS ONE” Your lifestyle and health can affect your chances of getting COVID-19; not enough sleep, lots of exercise, and hair loss can increase risk, while washing hands, eating fruit daily, and taking vitamins A and C can lower it.
14 citations,
January 2014 in “Anais Brasileiros de Dermatologia” Low BMI and cold exposure increase the risk of chilblains.
11 citations,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
10 citations,
February 2013 in “British Journal of Dermatology” Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
9 citations,
January 2018 in “Indian Journal of Endocrinology and Metabolism” Androgenetic alopecia is significantly linked to metabolic syndrome.
6 citations,
November 2019 in “The application of clinical genetics” The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
5 citations,
December 2016 in “Journal of skin and stem cell” People with cutaneous Lichen Planus are more likely to have Metabolic Syndrome and related conditions like high cholesterol, diabetes, and high blood pressure.
2 citations,
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.
2 citations,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
1 citations,
February 2023 in “Ibrain” Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.
1 citations,
August 2022 in “BMC Plant Biology” Melatonin helps broccoli roots produce anti-cancer compounds by controlling nitric oxide and hydrogen peroxide levels.
May 2020 in “Research Square (Research Square)” Women with PCOS have lower physical health quality of life than those without.
June 2024 in “Journal of Cosmetic Dermatology” Higher homocysteine levels may inhibit hair growth and are linked to androgenetic alopecia.
February 2024 in “Animals” Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.
March 2022 in “Molecules” Adenosine can help treat hair loss by promoting hair growth.
140 citations,
February 2020 in “Frontiers in Plant Science” RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.
96 citations,
December 2018 in “Immunity” Targeting TGFβ can improve skin immunity in older people.
82 citations,
October 2019 in “Frontiers in Immunology” Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.
77 citations,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
54 citations,
December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
23 citations,
October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
23 citations,
December 2013 in “Molecular cancer therapeutics” Breast cancer treatments work better with AR activation, improving results and reducing side effects.
20 citations,
January 2019 in “International journal of trichology” People with Alopecia areata often have lower Vitamin D levels, which might affect the severity of their condition.
18 citations,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.