This study found that adverse effects from hormonal contraception were more common and severe with progestin-only injections compared to estradiol levonorgestrel combination pills.
January 2017 in “Bulletin of Pharmaceutical Research” This study developed chemical fingerprints to differentiate Eclipta prostrata and Wedelia calendulacea, two plants often confused and adulterated in the Indian herbal market, identifying distinct chemical profiles that can prevent such adulteration.
78 citations
,
January 2000 in “Gynecological Endocrinology” This study found that the progestins norgestimate and dienogest may help treat clinical hyperandrogeny in women by inhibiting skin 5 alpha-reductase activity with minimal androgenic potential.
68 citations
,
May 1991 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that both cyproterone acetate and spironolactone effectively reduced hair diameter and plasma testosterone levels in hirsute women, with no significant differences between the two treatments.
61 citations
,
January 1970 in “Toxicology and Applied Pharmacology”
25 citations
,
October 2019 in “Journal of Endocrinological Investigation” This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.
50 citations
,
July 2001 in “PubMed” This study suggests a potential link between early-onset baldness before age 30 and increased risk for coronary artery disease, warranting consideration in epidemiological research.
49 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” This study found that combining cyproterone acetate with testosterone enanthate was highly effective in suppressing spermatogenesis, suggesting potential as a reversible male contraceptive method.
January 2022 in “Clinical Cases in Dermatology” This review discusses drug-induced alopecia, highlighting challenges in diagnosis and available therapies, and reports no new clinical results; the authors emphasize the need for further research into effective treatments.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
1 citations
,
March 2011 in “Hospital Pharmacy” This article highlights the importance of recognizing, preventing, and reporting adverse drug reactions to the FDA's MedWatch program, but it presents no new research findings.
20 citations
,
August 2022 in “Archives of Medical Science” This publication discusses the 2021 ESC Guidelines for the prevention of cardiovascular disease in clinical practice and reports no new results.
150 citations
,
February 2008 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study suggests that antiandrogens may slightly reduce hirsutism severity compared to placebo, but evidence is weak and their relative efficacy remains uncertain.
98 citations
,
May 2010 in “British Journal of Dermatology” This document discusses the British Association of Dermatologists' current perspective on isotretinoin, focusing on its known side effects, prescribing requirements, teratogenic risks, and the contentious link to mood changes, reporting no new research findings.
94 citations
,
July 1991 in “Clinical endocrinology” In this study, cyproterone acetate at 2 mg daily was found to be as effective as higher doses in reducing hair growth for hirsute women over 12 months.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.
42 citations
,
September 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the distinct clinical and psychological aspects of adult female acne and reports no new clinical results, highlighting the need for a comprehensive management approach.
41 citations
,
June 2010 in “Anais Brasileiros de Dermatologia” This study found that isotretinoin is a safe and well-tolerated acne treatment, with common adverse effects like cheilitis manageable through symptomatic medication and no significant changes in lipid or liver enzyme levels.
34 citations
,
June 2010 in “Archives of Disease in Childhood” This review discusses normal menstrual variations and common menstrual disorders in adolescent girls, focusing on symptoms, evaluation, and management, but does not present new clinical results.
33 citations
,
January 2009 in “Contraception” This review summarizes the use of chlormadinone acetate for hormone replacement therapy and contraception, highlighting its anti-androgenic effects, contraceptive efficacy, and clinical tolerability, without offering new clinical results.
18 citations
,
June 2010 in “Current medicinal chemistry” This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.
13 citations
,
May 1993 in “International Journal of Dermatology” This article presents a theory on the causes and development of telogen effluvium and reports no new clinical findings.
10 citations
,
January 2017 in “The World Allergy Organization journal” This article collection reviews the significant influence of gender and sexual hormones on allergies and asthma, noting more severe symptoms in females and the role of estrogen.
10 citations
,
January 2015 in “Przeglad Menopauzalny” This review discusses the effects and selection criteria of different progestogens in various treatments but reports no direct clinical comparisons of their metabolic effects.
8 citations
,
January 1987 in “Gynecological Endocrinology” This study found that treatment with the pure antiandrogen Flutamide did not affect the estrous cycle or plasma levels of most hormones in female rats, supporting its potential use for treating hirsutism, acne, and alopecia in women.
6 citations
,
October 2016 in “Contraception” This study found that most UK women prescribed cyproterone acetate/ethinylestradiol before and after 2013 had conditions aligning with approved indications and prior acne treatment.
1 citations
,
March 2013 in “The European Journal of Contraception & Reproductive Health Care” This publication discusses the political rationale behind the French regulator ANSM's decision to withdraw Diane®-35 from the market, in response to health concerns associated with third-generation oral contraceptives.
1 citations
,
January 2011 This study discusses the physiopathogeny, clinical manifestations, and treatment objectives of androgenetic alopecia without reporting new clinical findings.
1 citations
,
October 2006 in “Journal of Family Planning and Reproductive Health Care” This case report describes a woman who developed a 5 cm patch of scalp hair loss four months after receiving an Implanon contraceptive implant, with no previous history of hair loss or scalp issues.