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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Special fiber materials boost the healing properties of certain stem cells.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogen therapy can reduce skin aging but has cancer risks.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Understanding the mouse hair cycle is crucial for cancer research.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Skin fat helps with body temperature control and has other active roles in health.

The document concludes that molluscum contagiosum is a common, benign skin infection in children, often healing without scarring.