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This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.

This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.

This study used single-cell ATAC sequencing to map chromatin accessibility in developing mouse hair follicles, offering insights into the transcriptional regulation and epigenetic mechanisms underlying hair follicle development.

This study used single-cell RNA sequencing to characterize 19 distinct cell populations in sheep hair follicles, uncovering differentiation signatures and intercellular communication that may influence wool curvature and sheep breeding.

This study details a step-by-step protocol for preparing mammalian skin samples, including hair follicles, for spatial transcriptomics to overcome challenges inherent in applying this technique to the skin.

This study presents iSiMPRe, a method identifying protein regions enriched in mutations, revealing potential cancer-related genes and enhancing understanding of mutation effects across a wide range of cancer types.

This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.

This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.

This study identified and updated the annotation of 61 keratin genes in dogs and horses, improving the genome annotation in these species through RNA-seq data comparison.

This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.

In this study, researchers used transcriptome sequencing to identify various noncoding RNAs in the skin tissues of Jiangnan cashmere goats and found that certain long noncoding RNAs may play a role in regulating cashmere fiber fineness, offering new insights for breeding programs.

This study investigated adenosine-to-inosine RNA editing in the hair follicle cycle of Tianzhu white yak, identifying numerous editing sites and suggesting their involvement in pathways related to hair growth.

This study used single-cell RNA sequencing to identify at least nine subpopulations of keratinocytes in human neonatal epidermis, revealing unexpected heterogeneity and complex differentiation trajectories.

This article introduces signatureSearch, a software package designed for gene expression signature searching and functional enrichment analysis, but reports no new clinical results.

This study identified a genetic locus associated with coat type in domestic dogs, showing certain variants linked to single-coated breeds and suggesting potential regulatory roles.

This case report describes an 8 cm giant pilomatricoma on a 67-year-old man's scalp, revealing distinct transcriptional patterns related to hair follicle factors and keratin through spatial gene expression analysis.

This study examined the genetic basis for the curly hair trait in Mangalitza pigs, finding two specific genetic variants that contribute to this distinctive phenotype through autosomal dominant inheritance.

The researchers developed a comprehensive human skin cell atlas using data from various studies and established a consensus nomenclature for normal human skin in this project, which also includes a deep learning-based method for more effective reference mapping of new cells.

This study examined noninvasive tissue samples, including buccal swabs, hair follicles, saliva, and urine cell pellets, and found hair follicles and urine cell pellets promising for transcriptomic and clinical analyses due to their sample quality and performance in disease-relevant applications.

This study developed 3DEEP, a tissue clearing and spatial transcriptomic method, to map hair follicle development in a single time point from a 12-hour-old mouse, detailing molecular stages, signaling dynamics, and structural changes within developing follicles.

This study identified potential ceRNA regulatory networks in cashmere goat hair follicle cycling, expanding understanding of lncRNA and miRNA biology and annotation of the goat genome.

In this study, researchers found that hair follicle stem cells in mice can generate both hair follicle and epidermis cells, highlighting their potential bipotency.

This study identified two key pentapeptide quasi-repeats in human keratin-associated proteins, which are similar to motifs found in sheep wool.

This review discusses the genetic and environmental factors involved in the development of skin cancers like squamous cell carcinoma, basal cell carcinoma, and melanoma, but does not report new clinical findings.

In this case report, a 17-year-old male with a specific TRPS1 gene mutation presented with sparse, soft hair, short thumbs and toes, misaligned teeth, and distinctive bone abnormalities in the fingers and toes as observed through X-ray analysis.

In this study, researchers identified a novel biomarker of oxalate metabolism, which plays a crucial role in conditions like hyperoxaluria and kidney stones, marking the first time this detection has been reported.

This study analyzed the professional backgrounds of 4,405 aesthetic practitioners in the UK, revealing that 32% are doctors, 24% are dentists, and 13% are nurses, with significant representation from plastic surgery and dermatology among specialists.

This case study reports an unusual presentation of primary cutaneous diffuse large B-cell lymphoma–leg type occurring on the upper lip of an 81-year-old woman, highlighting the need for timely recognition of atypical manifestations.