92 citations
,
January 1999 in “Physics in Medicine and Biology” This study developed and validated a computational model to optimize skin precooling methods for minimizing thermal damage during laser procedures.
62 citations
,
February 2011 in “Expert review of dermatology” This review discusses the incidence, reversibility, and impact of chemotherapy-induced alopecia and concludes that scalp cooling is the most effective prevention method in most cases, though some questions remain.
4 citations
,
May 2024 in “Supportive Care in Cancer” In this survey study, participants from scalp cooling Facebook groups reported benefiting from shared experiences, instructions, insurance advice, and product recommendations, although only a minority sought dermatologist consultations, suggesting these groups provide a significant informational platform for chemotherapy-induced alopecia patients.
39 citations
,
January 1994 in “European Journal of Cancer” In this study, scalp hypothermia with the Theracool™ cooling machine was largely ineffective for preventing alopecia in breast cancer patients undergoing a chemotherapeutic regimen including cyclophosphamide and anthracyclines.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
June 2026 in “Pathology & Oncology Research” In this study, the Orbis PAXMAN® scalp cooling system showed effectiveness and good tolerability in preventing chemotherapy-induced hair loss in breast cancer patients, particularly those receiving anthracycline-free chemotherapy, though the presence of comorbidities was linked to a higher risk of severe alopecia.
52 citations
,
May 2013 in “Supportive Care in Cancer” Scalp cooling significantly reduces hair loss in chemotherapy patients.
7 citations
,
May 2014 in “Clinical practice” This article reviews drug-induced hair and nail disorders and discusses their clinical recognition, underlying mechanisms, and potential treatment strategies, without presenting new research findings.
January 1987 in “Side effects of drugs annual” This chapter reviews dermatological drugs and cosmetics, identifying common allergens and preservatives linked to contact dermatitis without reporting new clinical results.
3 citations
,
April 2017 in “Dermatologic Surgery” Laser hair removal can be an effective last-resort treatment for men with stubborn Alopecia Areata who want to be uniformly bald.
150 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
183 citations
,
January 2018 in “Cosmetics” This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.
141 citations
,
September 2016 in “European Journal of Dermatology” This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.
97 citations
,
September 2006 in “Pharmaceutical Research” This review discusses advances in protecting against chemotherapy-induced alopecia and reports no new clinical results; calcitriol and cyclosporine A emerged as promising agents in animal models with broader efficacy across multiple chemotherapy drugs.
48 citations
,
February 2017 in “Journal of Cosmetic Dermatology” This proposal reviews current knowledge and suggests actions for managing chemotherapy‐induced alopecia but reports no new clinical results, highlighting the need for evidence‐based guidelines.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” This article discusses the need for rational strategies in developing hair loss drugs targeting specific events in hair follicle cycling, reporting no clinical findings but emphasizing the importance of understanding molecular controls.
38 citations
,
September 2017 in “Oncologist” This source reports that scalp cooling is currently the only safe and FDA-cleared method to potentially reduce chemotherapy-induced hair loss, with about a 50% chance of maintaining sufficient hair to avoid needing a wig.
34 citations
,
January 2018 in “International Journal of Dermatology” This review discusses chemotherapy-induced alopecia, highlighting its pathogenesis, clinical patterns, and current therapeutic approaches, with no new clinical results reported.
14 citations
,
January 1985 in “International Journal of Dermatology” The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
8 citations
,
February 2012 in “International Journal of Dermatology” This review discusses skin problems common among long-distance runners and outlines helpful treatments, without presenting new clinical results.
6 citations
,
April 2022 in “The Breast” This study found that scalp cooling significantly reduced chemotherapy-induced hair loss in breast cancer patients, especially those receiving taxane monotherapy, but did not significantly affect hair regrowth after chemotherapy.
3 citations
,
November 2018 in “Oncology issues” This article discusses the emerging field of supportive oncodermatology, which collaborates between oncology and dermatology to address skin-related side effects of cancer treatments, and reports no new clinical results.
3 citations
,
January 2012 in “Elsevier eBooks” The document says that there are treatments for hair and nail diseases.
2 citations
,
October 2016 This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.
1 citations
,
January 2015 in “Springer eBooks” Chemotherapy can cause skin side effects that affect patients' lives, but they can be managed to avoid interrupting cancer treatment.
April 2026 in “The Breast” This study found that both scalp cooling systems and chemical cooling caps effectively reduced chemotherapy-induced alopecia in early breast cancer patients, with scalp cooling showing better early efficacy but chemical cooling providing greater psychological and quality of life benefits.
January 2026 in “Supportive Care in Cancer” This narrative systematic review reports that gel-based, cryogel, and silicone-based cooling caps offer cost-effective and environmentally sustainable alternatives to traditional machine-operated systems for preventing chemotherapy-induced hair loss, particularly benefiting low-income and low-resource settings.
October 2025 in “Journal of Drug Delivery Science and Technology” This study suggests that combining scalp cooling with resveratrol-loaded nanoparticles effectively protects hair follicles from chemotherapy-induced damage, highlighting a potential method to prevent hair loss during cancer treatment.
July 2014 in “Elsevier eBooks” The document concludes that various hypersensitivity diseases in horses can be diagnosed and treated with methods like immunotherapy and medication, and early aggressive treatment is crucial for severe diseases like equine cutaneous pythiosis.
October 2001 in “WORLD SCIENTIFIC eBooks” This compilation on contact and occupational dermatology in the Asia-Pacific region discusses various allergens and irritants without reporting new clinical findings.