Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study observed that the mechanical connection between hair follicles and connective tissue in human fetal scalp skin is weaker than in the corresponding skin components, reflecting dynamic processes in hair growth.

This article reviews the effectiveness of adrenal cortex compounds E and F in treating various connective tissue disorders and reports no new clinical findings.

This article discusses the effectiveness of adrenal cortex compounds E and F in treating connective tissue disorders like rheumatoid arthritis and lupus erythematosus, but it reports no new clinical results.

This chapter reviews the complexity of hair and wool follicle formation, emphasizing the importance of cytological studies to understand the relationship between cellular components.

This review discusses the various stem cell populations associated with hair follicles and their potential in regenerative medicine, highlighting differences between murine and human hair follicles but reports no new clinical results.

In this study, researchers developed a three-dimensional ultrastructural analysis tool using serial block-face scanning electron microscopy to reveal detailed nerve networks and muscle structures in human skin tissues, demonstrating the technique's potential to study structural changes in aging or disease.

This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.

This study identified collagen XXII as a novel extracellular matrix protein specifically present at tissue junctions, where it functions as a cell adhesion ligand for skin epithelial cells and fibroblasts.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This study found that the KrasG12D mutation alters ERK signal dynamics in hair follicle stem cells, leading to tissue deformation, and suggests a collective effect of mutant cells is necessary for disruption.

This study found that deleting the Mof gene in mouse skin leads to severe defects in skin cell self-renewal, differentiation, and hair follicle growth, indicating that MOF is crucial for mitochondrial and ciliary gene expression and essential for skin development.

This review explores the diverse roles and heterogeneity of fibroblasts across different organs, highlighting their potential involvement in both normal tissue functioning and fibrotic diseases, but reports no new experimental results.

This chapter reviews keratins in skin epithelia, including their roles in cellular function and disease, and reports no new experimental results.

This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

Keratins are crucial for cell structure, growth, and disease risk.

This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.

In this study, researchers found that epithelial cells exhibit density-dependent metabolic heterogeneity, particularly in the pre-epithelial transition stage, where metabolic patterns correlate with cell proliferation and are influenced by actomyosin contractility.

This essay shares the scientific pursuits and leadership approaches of the author's lab but presents no new research findings.

This review discusses how immune mechanisms contribute to the regeneration and repair of epithelial tissues and highlights their potential role in both disease and therapeutic innovation; it reports no new clinical results.

In this study, researchers found that the expression of vimentin, desmin, and laminin in rat skin contributes to cell structure and tissue integrity, with varying reactions across different cell types.

This review examines recent developments in tooth regeneration therapies using mesenchymal stem cells, but it reports no new clinical findings.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

This study demonstrates that Wnt signaling plays a crucial mechanoregulatory role in skin regeneration by influencing cellular responses to substrate rigidity, which promotes hair follicle regeneration in the wound-induced hair neogenesis model.

This study identified WNT10A as crucial for adult epithelial cell proliferation and differentiation, suggesting β-catenin pathway activation may help address regenerative defects in WNT10A mutation patients.

This review explores the infundibulum's role and importance in skin diseases and emphasizes the need for further research into its biology and potential therapeutic targeting, but it presents no new findings.

This study found that in anagen hair follicles, the basement membrane zone components showed decreased expression in the lower hair bulb, with a complete absence of BP230 at the dermal papilla junction, suggesting an incomplete hemidesmosome structure in these regions.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.

This study found that local refinement of hair follicles into higher order patterns can occur without the core planar cell polarity system, but global alignment with body axes requires its function throughout development and regeneration.