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Progerin affects cell shape but not hair or skin in mice.

The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Muscles can make their own androgens, which may help muscle growth.

The document covers all aspects of plastic and reconstructive surgery, from basic techniques to specific procedures for various body parts.

Notch signaling disruptions can cause various skin diseases.

Women with female pattern hair loss have lower Vitamin D3 levels.

Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Acyzol could help treat conditions caused by zinc deficiency.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.

Some vitamins and minerals are important for preventing hair loss, but treating hair loss with them without a known deficiency is not proven effective.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

A Nigerian baby with neonatal lupus got better with treatment by 6 months.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

Some women with PCOS have rare genetic variants linked to the condition.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Certain skin proteins can form anchoring structures without the protein AMACO.

The UK's EDS National Diagnostic Service found that early diagnosis, lifestyle advice, and regular check-ups are crucial for managing vascular Ehlers-Danlos syndrome. A combination of losartan and bisoprolol can reduce vascular events, improving survival and quality of life.

A new mutation in the MBTPS2 gene causes a mild form of IFAP syndrome.

Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.