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Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

New treatments targeting specific genes show promise for treating keratin disorders.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Zinc supplements increased zinc levels in some hair loss patients but didn't significantly improve hair growth.