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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.