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The junction of the inner and outer prepuce with good blood flow is ideal for surgical flaps.

The junction of the inner and outer prepuce with good blood flow is best for vascular pedicle flaps.

Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.

Gene mutations can cause problems in male genital development.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Using buccal mucosa for hypospadias repair in children is effective and reduces complications.

Using a laser to remove hair in the urethra after hypospadias repair is effective and minimally invasive.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.

Flutamide-induced hypospadias in rats slows down early wound healing.

Hormone treatment before hypospadias surgery can increase penis size and reduce surgery complications.

Untreated congenital adrenal hyperplasia can lead to complications like stroke and needs glucocorticoid treatment.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Genetic mutations can affect female sexual development, requiring personalized medical care.

A boy with a rare birthmark called verrucous hemangioma needed careful timing for surgery due to its size and depth.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Conditions affecting sex development show that sexual diversity is a natural part of human variation.

New treatments for male hypogonadism are effective and should be personalized.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Baby born healthy despite mom taking finasteride, but more research needed.