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      Pityrosporum Species as a Cause of Allergy and Infection

      research Pityrosporum species as a cause of allergy and infection

      89 citations , May 1999 in “Allergy”
      This article reviews the role of Pityrosporum (Malassezia) in skin conditions such as pityriasis versicolor, seborrheic dermatitis, and atopic dermatitis, and discusses treatment approaches; it reports no new clinical results.
      The Pathogenesis of Alopecia Areata

      research THE PATHOGENESIS OF ALOPECIA AREATA

      89 citations , October 1996 in “Dermatologic Clinics”
      This review discusses androgenetic alopecia and alopecia areata through a systems biology lens, emphasizing the role of multi-omics data integration to explore molecular mechanisms and potential therapeutic strategies, but offers no new clinical results.
      Physiological Functions of PP2A: Lessons from Genetically Modified Mice

      research Physiologic functions of PP2A: Lessons from genetically modified mice

      87 citations , July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research”
      This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.
      The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

      research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle

      87 citations , July 2009 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.
      Evaluation and Diagnosis of the Hair Loss Patient

      research Evaluation and diagnosis of the hair loss patient

      86 citations , August 2014 in “Journal of The American Academy of Dermatology”
      This article discusses the history taking and clinical examination process for diagnosing alopecia and outlines a diagnostic approach, noting that it reports no new clinical results.
      An Integrative View of Mammalian Seasonal Neuroendocrinology

      research An integrative view of mammalian seasonal neuroendocrinology

      85 citations , May 2019 in “Journal of neuroendocrinology”
      This review examines the neuroendocrine mechanisms underlying seasonal changes in mammals and highlights areas needing further research, reporting no new experimental results.
      The Blastema and Epimorphic Regeneration in Mammals

      research The blastema and epimorphic regeneration in mammals

      85 citations , December 2017 in “Developmental Biology”
      This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
      Keratin K15 as a Biomarker of Epidermal Stem Cells

      research Keratin K15 as a Biomarker of Epidermal Stem Cells

      85 citations , September 2013 in “International Journal of Molecular Sciences”
      This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.
      Development and Homeostasis of the Skin Epidermis

      research Development and Homeostasis of the Skin Epidermis

      85 citations , July 2012 in “Cold Spring Harbor perspectives in biology”
      This article discusses the roles of epidermal stem cells in maintaining skin homeostasis and highlights how deregulation in signaling pathways may lead to cancer, but it reports no new experimental results.
      Drug Reactions Affecting Hair: Diagnosis

      research Drug Reactions Affecting Hair: Diagnosis

      85 citations , April 2007 in “Dermatologic Clinics”
      This article reviews drug-induced hair changes, highlighting that while many drugs are occasionally linked to hair loss, this connection has been conclusively established for only a few, and such hair loss is typically reversible.
      Molecular Regulation of Melanocyte Senescence

      research Molecular Regulation of Melanocyte Senescence

      85 citations , July 2002 in “Pigment Cell Research”
      This review examines cell senescence pathways in melanocytes, highlighting the involvement of telomere attrition, the p16/RB pathway, and cAMP signaling in the context of melanoma development, but reports no new findings.
      A Dubious Equality: Men, Women, and Cosmetic Surgery

      research `A Dubious Equality': Men, Women and Cosmetic Surgery

      85 citations , March 2002 in “Body & Society”
      This article reviews the discourse around male cosmetic surgery patients and argues against the perception that cosmetic surgery will become as common among men as it is among women.
      Ritlecitinib: First Approval

      research Ritlecitinib: First Approval

      84 citations , August 2023 in “Drugs”
      This article describes the development milestones and recent approvals of ritlecitinib for treating severe alopecia areata, with approvals in the USA and Japan and ongoing regulatory reviews in other regions.
      Building Epithelial Tissues From Skin Stem Cells

      research Building Epithelial Tissues from Skin Stem Cells

      84 citations , January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology”
      This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
      Human αβ and γδ T Cells in Skin Immunity and Disease

      research Human αβ and γδ T Cells in Skin Immunity and Disease

      83 citations , June 2018 in “Frontiers in immunology”
      This review discusses the roles of αβ and γδ T cells in skin health and disease and reports no new clinical results; the authors highlight potential therapeutic developments.
      Intracrinology and the Skin

      research Intracrinology and The Skin

      82 citations , January 2000 in “Hormone Research in Paediatrics”
      This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.
      Diversification and Specialization of Touch Receptors in Skin

      research Diversification and Specialization of Touch Receptors in Skin

      81 citations , June 2014 in “Cold Spring Harbor perspectives in medicine”
      This article discusses recent advances in understanding the mechanisms of tactile end organs in the epidermis and hair follicles from studies of mouse hairy skin, but it reports no new clinical results.
      Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification

      research Inherited ichthyoses/generalized Mendelian disorders of cornification

      81 citations , June 2012 in “European journal of human genetics”
      This review outlines a diagnostic framework for clinicians to distinguish different types of inherited ichthyoses and suggests further testing and treatment strategies, but reports no new clinical results.
      Eating Disorders: Progress and Challenges

      research Eating Disorders: Progress and Challenges

      81 citations , January 2011 in “European Journal of Internal Medicine”
      This review updates on the understanding and management of eating disorders, noting substantial progress over 30 years but highlighting the need for revised classification, clarified pathogenesis, and improved treatments.