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Not having enough cystatin M/E protein causes less hair growth and dry skin.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Fatty acid transport protein 4 is essential for skin and hair development.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Mice with CBS deficiency are healthier on a low-methionine diet.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

Blocking interferon-gamma might help treat various autoimmune diseases.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.

Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.