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Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Stem cell niches support, regulate, and coordinate stem cell functions.

K16 can partially replace K14 but causes hair loss and skin issues.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

TGFβ signaling prevents sebaceous gland cells from producing fats.

A special receptor in sensory nerve endings helps control how they respond to stretching.

Th22 cells are essential for Tβ15-induced hair growth in mice.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

New mouse models of Pemphigus show severe symptoms and need better treatments.

Radiation significantly slows down wound healing in mice.

Rumex japonicus extract may promote hair growth more effectively than Minoxidil.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.