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Controlling Tslp can improve health in AEC syndrome patients.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Meis2 is essential for touch sensation and nerve function in mice.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.

miR-29 is a key factor that accelerates aging.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Sox2 controls hair color by affecting pigment production in hair follicles.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.

New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.

Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.