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This study reports two cases of acquired zinc deficiency presenting with skin symptoms such as hair loss and acrodermatitis, suggesting these manifestations may help in diagnosing zinc deficiency in humans.

This study found that Wnt secretion is important for maintaining skin homeostasis in mice, as Evi-deficient mice developed psoriasis-like skin lesions and had an imbalance in immune cell populations.

In this study, a syndrome of zinc deficiency was observed in adults receiving intravenous feeding, with zinc supplementation improving symptoms except for delayed hair regrowth.

This study identified a gene mutation in the LIPH gene associated with inherited hair loss and hair growth defects in certain populations, suggesting lipase H plays a role in hair development.

This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.

This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.

This study found that while biotin treatment improves clinical and biochemical symptoms in patients with biotinidase deficiency, some experience lasting neurological damage, and it is uncertain if early treatment can prevent this.

This review discusses the emerging "endocrine phenotype" of COVID-19, highlighting the implications for managing diabetes, obesity, vitamin D deficiency, and other endocrine conditions in affected patients.

In this study, researchers observed vitamin D insufficiency in many patients with Alopecia Areata, suggesting its potential role in managing this autoimmune condition.

This study found that patients with alopecia areata had significant systemic inflammation and vitamin D deficiency, with both conditions more pronounced as disease severity increased.

In this study, researchers identified a novel congenital skin disorder in Chesapeake Bay retrievers, linked to a plakophilin-1 deficiency due to a genetic mutation, marking the first known occurrence in an animal species.

This study found that the absence of sebaceous glands may be an early factor in the development of keratosis pilaris, leading to hair shaft and skin barrier abnormalities, independent of filaggrin mutations.

This report describes a child with ulerythema ophryogenes marked by eyebrow hair absence and progressive skin atrophy, whose condition did not improve despite elevated vitamin A levels via injections.

This article discusses nutritional contributions to hair health and highlights the need for identifying risk factors for deficiencies but reports no new clinical findings.

This study found that segmented heterochromic scalp hair associated with iron-deficiency anemia in a teenage girl completely recovered following iron supplementation, suggesting a role for iron in hair pigment production.

Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.

This study found that maternal iron-restricted diets increased alopecia incidence in IL-10-deficient mouse pups with mast cells, implicating mast cells as potential effectors in this process.

This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.

This study observed a high incidence of transient infantile zinc deficiency among breastfeeding infants in Northern Ethiopia, but could not determine if genetic or nutritional factors or both contributed to it.

This study found a significant correlation between vitamin D deficiency and the severity of androgenetic alopecia in males, suggesting that vitamin D may influence the condition's premature onset.

This commentary critiques the definition of iron deficiency in hair loss studies, suggesting higher serum ferritin levels as a more accurate threshold for diagnosing deficiency in women.

This study observed that patients with autism spectrum disorder have a higher risk of developing alopecia areata compared to those without ASD, suggesting a possible link between the two conditions.

This review explores the potential roles of the gut and skin microbiome in alopecia areata, suggesting topical and systemic strategies for managing the condition, but it reports no new clinical results.

In this case study, a 45-year-old woman's hair loss improved after three months of weekly high-dose vitamin D supplementation, emphasizing the importance of assessing vitamin D levels in patients with hair loss.

In this case report, a patient with pseudovaginal perineoscrotal hypospadias due to 5α-reductase deficiency presented gender dysphoria, and after genomic sequencing confirmation, injectable testosterone undecanoate treatment successfully developed desired male secondary sexual characteristics.

This chapter discusses various aspects of collagen, proposing "extended collagen carential disease" as a new concept tied to nutritional deficiencies, notably Vitamin C's role in maintaining collagen health.

This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.

In this case report, a 6-year-old male with biotinidase deficiency experienced marked improvement in dermatological symptoms, including alopecia and periorificial lesions, following biotin treatment.

In this study, researchers found that deficiencies in Gsdma1/2/3 significantly inhibited the initiation and progression of cutaneous squamous cell carcinoma (cSCC) in mice, suggesting GSDMA's role in promoting cSCC proliferation and its potential as a therapeutic target.

In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.